Nuclear Receptors

Nuclear hormone receptors (nuclear receptors) are specialized transcription factors which bind to specific sequences of DNA of particular target genes. They regulate transcription of these target genes in response to a variety of endogenous ligands. Nuclear receptors are classified into two major subfamilies: steroid and non-steroid hormone receptors. Steroid hormone receptors include receptors for estrogen (ER), androgen, glucocorticoid, mineralocorticoid and progesterone. Examples of non-steroid hormone receptors include thyroid receptors, retinoic acid receptors and peroxisome proliferator-activated receptors (PPAR). Researchers can make big savings on Hello Bio's Nuclear Receptors agonists, antagonists and modulators (e.g. tamoxifen, 4-OHT, fulvestrant, DPN, PPT), our prices are around 25-50% less than other suppliers.

View products: Aryl hydrocarbon receptor | Estrogen and related | Liver X and farnesoid X receptors (LXR/FXR) | Glucocorticoid Mineralocorticoid | Other | PPAR | Progesterone

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10 Items

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  1. Calphostin C (HB0160)

    Description:

    Potent, selective PKC inhibitor. Also antagonizes the Tcf/β-catenin complex

    Purity:

    >95%

    Pack:
    100μg
    Price:
    $239
    Qty:
    Pack:
    1mg
    Price:
    $1,215
    Qty:
  2. Pack:
    50mg
    Price:
    $521
    Qty:
  3. Fz7-21 (HB8797)

    Description:

    Selective FZD7 (Frizzled 7 receptor) antagonist

    Pack:
    1mg
    Price:
    $204
    Qty:
  4. ICG 001 (HB0331)

    Description:

    Selective, competitive inhibitor of β-catenin/CBP interaction

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $237
    Qty:
  5. IWP 2 (HB0344)

    Description:

    Potent Wnt pathway inhibitor and PORCN inhibitor. Suppresses R1 ESC self-renewal. Used in the production of cardiac organoids.

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $370
    Qty:
  6. IWP 4 (HB3066)

    Description:

    Potent Wnt/β-catenin signaling inhibitor. Induces cardiomyocyte differentiation of hESCs and iPSCs.

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $550
    Qty:
  7. PNU 74654 (HB0528)

    Description:

    β-catenin inhibitor. Wnt pathway inhibitor. Promotes neural differentiation of hPSCs.

    Purity:

    >99%

    Pack:
    50mg
    Price:
    $591
    Qty:
  8. TAK 715 (HB0599)

    Description:

    Potent, p-38 MAP kinase inhibitor. Wnt/β-catenin signaling inhibitor.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $188
    Qty:
    Pack:
    50mg
    Price:
    $743
    Qty:
  9. Pack:
    5mg
    Price:
    $94
    Qty:
    Pack:
    25mg
    Price:
    $365
    Qty:
  10. XAV 939 (HB0660)

    Description:

    Potent tankyrase inhibitor. Wnt/β-catenin signaling inhibitor.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    Qty:
    Pack:
    10mg
    Price:
    $115
    Qty:
    Pack:
    25mg
    Price:
    $257
    Qty:
    Pack:
    50mg
    Price:
    $465
    Qty: