GABA receptor agonists, antagonists and modulators - low cost, high quality

GABA receptors are classified into GABA_A receptors which are ligand-gated ion channels (or ionotropic receptors) and GABA_B receptors, which are G protein-coupled receptors (metabotropic receptors). GABA_A receptors are members of the Cys-loop family that also include the nicotinic acetylcholine, 5-HT₃ and strychnine-sensitive glycine receptors. GABA_A receptors exist as pentamers of 4TM subunits that form an intrinsic anion selective channel. Sequences of six α, three β, three γ, one δ, three ρ, one ε, one π and one θ GABA_A receptor subunits have been reported in mammals. Receptors formed from ρ-subunits have a distinctive pharmacology (eg.insensitivity to bicuculline, benzodiazepines and barbiturates), and have sometimes been termed GABA_C receptors. However they are now classified as GABA_A receptors ( GABA_A-ρ subclass)  by NC-IUPHAR,  based on structural and functional criteria. GABA_B receptors are G protein-coupled receptors that are composed of  GABA_B1 and GABA_B2 subunits, which form the core of the receptor, and auxiliary K-channel tetramerization domain (KCTD) subunits.

As a specialist supplier of affordable GABA receptor research tools, Hello Bio has introduced a range of low-cost agonists, antagonists and modulators for GABA_A and GABA_B receptors - at prices up to 50% less than other suppliers.

Our GABA receptor range includes standard tools such as the GABA_A- antagonists SR95531 (gabazine) and bicuculline methochloride  together with cutting edge products such as  Cmpd101, a new tool for studying GPCR desensitisation.

Browse our full range of GABA receptor agonists, antagonists and modulators below:

GABA receptors	Related ligand gated ion channels		Related GPCRs
GABAA GABAB GABA transport and uptake	NMDA AMPA Kainate		Adrenoceptors Ach muscarinic Cannabinoid GHB 5-HT Histamine Metabotropic glutamate Opioid Prostanoid

Highest quality

Our prices are up to 50% less than other suppliers (view price comparison table). However, we know that product reliability is more important than price. We are based in purpose built labs in the UK and with decades of synthetic and manufacturing chemistry expertise we know what we are doing! For your peace of mind, all of our products are covered by the Hello BioPromise quality guarantee.