Differentiation

Stem cells such as induced pluripotent stem cells (iPSCs) and human embryonic stem (ESCs) are differentiated into specialized cell types for applications including drug discovery, disease modeling and cell therapy. Small molecules such as DAPT, A83-01, dexamethasone, may be used to modulate signaling pathways which affect stem cell differentiation. Researchers can save up to 50% on high purity stem cell differentiation research products - they are up to half the price of other suppliers.

View products: iPSCs & ESCs | Mesenchymal Stem cells (MSCs) | Neural Stem Cells (NSCs)

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A83-01 (HB3218)

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Description:
Selective TGF-βRI (ALK5), ALK4 and ALK7 inhibitor. Maintains human hiPSC self renewal, 3D growth matrix component and promotes long-term organoid growth. Aids fibroblast to NSC/cardiomyocyte reprogramming.

Purity:
>98%

Pack:
5mg
Price:

$92

Qty:

Pack:
25mg
Price:

$310

Qty:

Supporting Docs Add to Favorites

(+)-Abscisic acid (HB4674)

Description:
Phytohormone and endogenous lanthionine synthetase C-like 2 (LANCL2) ligand

Purity:
>99%
Pack:
10mg
Price:

$143
Free trial

Qty:
We offer a Free Trial Program for both our loyal customers and those researchers who are new to Hello Bio!

To receive any free trial offers that you are eligible for, you must be logged into your account.

If you are already a Hello Bio customer - unlimited* free trials!

When you see the Free Trial icon, simply add your chosen free trial to your basket, along with at least one other product.

To order direct, log in to your account and at checkout enter the code FREETRIAL - your free trial pack will be discounted (see Terms & Conditions below). This will be itemized on your invoice.

If your purchasing team will be placing the order on your behalf, log in to your account, use the generate quote feature and enter the code FREETRIAL when prompted. Give the quote number to your purchasing team to include with the order, and your free trial pack will be discounted.

You can claim unlimited* free trials per calendar year, on selected products that you have not purchased previously.

You may only claim one free trial per order. See below for full Ts and Cs.

If you are new to Hello Bio - one free trial, plus free delivery!

If you have never purchased from Hello Bio before, we offer a Try Before You Buy! Simply Add your chosen Free Trial Pack to your basket, create an account and enter the code WELCOMEOFFER at Checkout. This is a no obligation offer and no other purchases are necessary. Your Free Trial will be discounted at Checkout and there will be no delivery to pay.

If your purchasing team will be placing the order on your behalf, log in to your account, use the generate quote feature and enter the code WELCOMEOFFER when prompted. Give the quote number to your purchasing team to include with the order, and your free trial pack will be discounted.

Using the Quote Generator?

If you are using the quote generator, and wish to access the Free Sample Program you must first log in to your account to enable any relevant free sample offers to appear. Please note, if you do not first log in, you may see offers that you are not eligible for. See below for full Ts and Cs.

Terms and conditions

*Free trials are only available on selected products. When there is a Free Trial available for a particular product it will be displayed on the product page.

You need to be a scientific researcher (or ordering on behalf of a scientific researcher) to access the Free Trial Program.

Researchers who have an online account and can be identified as previously having made a purchase from Hello Bio, either directly or indirectly via a purchasing team ("customers") will be eligible for unlimited* free trial products in 2024.

Researchers who have not made a prior purchase from Hello Bio are eligible for 1 free trial product with free delivery in 2024.

Researchers who have not made a prior purchase from Hello Bio must use their institutional email address (not a personal email address) when claiming their free trial.

Customers may only claim one free trial per order and may not claim the same free trial product more than once.

Customers can only claim free trial packs of products that they have not purchased previously.

This offer can’t be used with any other offers

This offer is not valid for resellers or Hello Bio distributors, and the free products are not for resale.

This offer is not valid for researchers placing their orders via a 3rd party (eg. distributors)

Free trial offers are only valid whilst stocks last.

If a Free Trial product is not in stock, no alternative product will be offered.

Researchers who access the Free Trial Program will receive a request for feedback about their free product, and a follow up email, which they can unsubscribe from at any time.

And finally - we do reserve the right to change these terms and conditions at any time!

If you have any other queries, just email customercare@hellobio.com (for customers in the UK, Europe and Rest of the World) or customercare-usa@hellobio.com (for customers in the USA & Canada) and we will be happy to help.
Pack:
50mg
Price:

$626

Qty:
Supporting Docs Add to Favorites

AICAR (HB2152)

Description:
AMPK activator. Promotes osteogenic differentiation of bone marrow-derived MSCs.

Purity:
>99%

Pack:
25mg
Price:

$83

Qty:

Supporting Docs Add to Favorites

L-Ascorbic acid (HB1238)

Description:
Antioxidant. Enhances iPSC generation and increases reprogramming efficiency. Supports mesenchymal stem cell proliferation.

Purity:
>99%

Pack:
100mg
Price:

$89

Qty:

Pack:
1g
Price:

$29

Qty:

Pack:
25g
Price:

$43

Qty:

Pack:
100g
Price:

$103

Qty:

Supporting Docs Add to Favorites

5-Azacytidine (HB1374)

Description:
DNA methyltransferase inhibitor. Improves stem cell reprogramming efficiency and induces differentiation of MSCs into cardiomyocytes.

Purity:
>98%

Pack:
50mg
Price:

$70

Qty:

Pack:
250mg
Price:

$97

Qty:

Supporting Docs Add to Favorites

Recombinant human BDNF protein (HB3485)

Description:
Member of the neurotrophin growth factor family. Plays an important role in synaptic plasticity and neurogenesis.

Pack:
2μg
Price:

$68

Qty:

Pack:
10μg
Price:

$271

Qty:

Supporting Docs Add to Favorites

CCG 1423 (HB3389)

Description:
Rho/SRF pathway inhibitor. Induces intermediate mesoderm differentiation from ESCs.

Purity:
>99%

Pack:
10mg
Price:

$117

Qty:

Pack:
50mg
Price:

$433

Qty:

Supporting Docs Add to Favorites

CHIR 99021 (HB1261)

Description:
Potent, selective GSK3 inhibitor and Wnt signaling activator. Commonly used in organoid production and involved in reprogramming MEFs to IPSCs and fibroblasts to mature neurons.

Purity:
>98%
Pack:
1mg
Price:

$50

Qty:

Pack:
2mg
Price:

$62
Free trial

Qty:
We offer a Free Trial Program for both our loyal customers and those researchers who are new to Hello Bio!

To receive any free trial offers that you are eligible for, you must be logged into your account.

If you are already a Hello Bio customer - unlimited* free trials!

When you see the Free Trial icon, simply add your chosen free trial to your basket, along with at least one other product.

To order direct, log in to your account and at checkout enter the code FREETRIAL - your free trial pack will be discounted (see Terms & Conditions below). This will be itemized on your invoice.

If your purchasing team will be placing the order on your behalf, log in to your account, use the generate quote feature and enter the code FREETRIAL when prompted. Give the quote number to your purchasing team to include with the order, and your free trial pack will be discounted.

You can claim unlimited* free trials per calendar year, on selected products that you have not purchased previously.

You may only claim one free trial per order. See below for full Ts and Cs.

If you are new to Hello Bio - one free trial, plus free delivery!

If you have never purchased from Hello Bio before, we offer a Try Before You Buy! Simply Add your chosen Free Trial Pack to your basket, create an account and enter the code WELCOMEOFFER at Checkout. This is a no obligation offer and no other purchases are necessary. Your Free Trial will be discounted at Checkout and there will be no delivery to pay.

If your purchasing team will be placing the order on your behalf, log in to your account, use the generate quote feature and enter the code WELCOMEOFFER when prompted. Give the quote number to your purchasing team to include with the order, and your free trial pack will be discounted.

Using the Quote Generator?

If you are using the quote generator, and wish to access the Free Sample Program you must first log in to your account to enable any relevant free sample offers to appear. Please note, if you do not first log in, you may see offers that you are not eligible for. See below for full Ts and Cs.

Terms and conditions

*Free trials are only available on selected products. When there is a Free Trial available for a particular product it will be displayed on the product page.

You need to be a scientific researcher (or ordering on behalf of a scientific researcher) to access the Free Trial Program.

Researchers who have an online account and can be identified as previously having made a purchase from Hello Bio, either directly or indirectly via a purchasing team ("customers") will be eligible for unlimited* free trial products in 2024.

Researchers who have not made a prior purchase from Hello Bio are eligible for 1 free trial product with free delivery in 2024.

Researchers who have not made a prior purchase from Hello Bio must use their institutional email address (not a personal email address) when claiming their free trial.

Customers may only claim one free trial per order and may not claim the same free trial product more than once.

Customers can only claim free trial packs of products that they have not purchased previously.

This offer can’t be used with any other offers

This offer is not valid for resellers or Hello Bio distributors, and the free products are not for resale.

This offer is not valid for researchers placing their orders via a 3rd party (eg. distributors)

Free trial offers are only valid whilst stocks last.

If a Free Trial product is not in stock, no alternative product will be offered.

Researchers who access the Free Trial Program will receive a request for feedback about their free product, and a follow up email, which they can unsubscribe from at any time.

And finally - we do reserve the right to change these terms and conditions at any time!

If you have any other queries, just email customercare@hellobio.com (for customers in the UK, Europe and Rest of the World) or customercare-usa@hellobio.com (for customers in the USA & Canada) and we will be happy to help.
Pack:
5×2mg
Price:

$188

Qty:

Pack:
10mg
Price:

$182

Qty:

Pack:
5mg
Price:

$117

Qty:

Pack:
25mg
Price:

$445

Qty:

Pack:
50mg
Price:

$758

Qty:

Pack:
10mM (1mL in DMSO)
Price:

$126

Qty:
Supporting Docs Add to Favorites

Compound E (HB3849)

Description:
Potent, selective, non-competitive γ-secretase inhibitor. Induces neuronal differentiation.

Purity:
>98%

Pack:
1mg
Price:

$389

Qty:

Supporting Docs Add to Favorites

Cyclopamine (HB2965)

Description:
Smo and hedgehog (Hh) signaling inhibitor. Also depletes stem like cancer cells and induces hESCs into endocrine cells.

Purity:
>98%

Pack:
1mg
Price:

$205

Qty:

Pack:
5mg
Price:

$779

Qty:

Supporting Docs Add to Favorites

Differentiation

A83-01 (HB3218)

(+)-Abscisic acid (HB4674)

If you are already a Hello Bio customer - unlimited* free trials!

If you are new to Hello Bio - one free trial, plus free delivery!

Using the Quote Generator?

Terms and conditions

AICAR (HB2152)

L-Ascorbic acid (HB1238)

5-Azacytidine (HB1374)

Recombinant human BDNF protein (HB3485)

CCG 1423 (HB3389)

CHIR 99021 (HB1261)

If you are already a Hello Bio customer - unlimited* free trials!

If you are new to Hello Bio - one free trial, plus free delivery!

Using the Quote Generator?

Terms and conditions

Compound E (HB3849)

Cyclopamine (HB2965)