CRISPR/ Gene editing
Small molecules such as 4-Hydroxytamoxifen ≥70% Z isomer can enhance the overall efficiency and targeting precision of CRISPR/Cas-9-mediated genome editing. Researchers can save up to 50% on small molecules for CRISPR / Cas9 genome editing - they are up to half the price of other suppliers.
(+)-Abscisic acid (HB4674)Description:
Phytohormone and endogenous lanthionine synthetase C-like 2 (LANCL2) ligandPurity:
Selective reverse transcriptase inhibitor with anti-HIV activity. Decreases CRISPR-mediated homology directed repair (HDR) and enhances gene knockout efficiency.
Brefeldin A (BFA) (HB2949)Description:
Reversible protein transport inhibitor. Commonly used in cytokine staining. Enhances CRISPR-mediated HDR.Purity:
Estrogen receptor ligand. For inducible genome manipulation (e.g. Cre-LoxP (CreER)/ TRAP/ CRISPR-Cas9).Purity:
Synthetic estrogen receptor ligand. Widely used in genome engineering (e.g. CreER/ CRISPR-Cas9).Purity:
Potent glucocorticoid and progesterone receptor antagonist. Also used for gene editing as a mifepristone inducible Cas9 and Cpf1 CRISPR effector.Purity:
Mitosis inhibitor, widely used as a cell cycle synchronizing agent. Enhances HDR efficiency and increases Cas9-mediated gene editing frequencies.Purity:
mTOR inhibitor and potent immunosuppressant. Also used in inducible gene editing methods (e.g. CRISPR/Cas9) and promotes hPSC differentiation.Purity: