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Enzymes
Isomerase
DNA Topoisomerase
DNA Gyrase

DNA Gyrase

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Simocyclinone D8 (HB4084)

Description:
Bacterial DNA gyrase inhibitor

Purity:
>97%

Pack:
1mg
Price:

$135

Qty:

Supporting Docs Add to Favorites

Understanding purity and quality - a guide for life scientists (159.4 KB)

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α3β4

α4β2

α7

Non-selective

PSEMS

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Non-selective

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Abl

Akt / PKB

AMPK

Aurora kinase

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Non-selective

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CAM Kinase II

Casein kinase

CDK

CDK1

CDK2

Non-selective

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DYRK

ERK

ERK2 / MAPK1

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Non-selective

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Hexokinase

JAK

MAPK

p38 MAPK

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MEK1

JNK

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Non-selective

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PKA

PKC

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Protein-tyrosine kinase

Non-selective

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RIP1

ROCK

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Sphingosine kinase

Syk

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Ubiquitin/Ubl E2 conjugating

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Monoamine Oxidase

Non-selective

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COX

COX-2

5-lipoxygenase

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PDE1

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Non-selective

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N-Smase

Phosphatase

Alkaline phosphatase

Phosphoprotein phosphatase

Protein Phosphatase 1 (PP1)

PP2A

Calcineurin / PP2B

PP4

Protein serine/threonine phosphatase (PSP)

CAPP (Ceramide-activated protein phosphatase)

Protein-tyrosine phosphatase

PTP1B

Polymerase

DNA/RNA

Tankyrase (TNKS)

Telomerase

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Aminopeptidase

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Aspartic protease

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Caspase

Broad

Cathepsin

Cathepsin B

Deubiquitinating Enzymes

Ubiquitin C-terminal hydrolase

Dipeptidyl-peptidase 4

Elastase

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γ

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Aldose reductase

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Synthase

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NOS

Transferase

ACAT

DGAT

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Histone acetyltransferase (HAT)

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PORCN

Tankyrase (TNKS)

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Actin

Choline ester transfer protein (CETP)

GAPDH

GFAP

GFP

Histones

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HSP60

MAP2

mCherry

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N-WASP

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IBA1

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PI3K

mTOR

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ROCK

TGF-Beta/ SMAD

MAPK

p38 MAPK

MEK

ERK

ERK2 / MAPK1

JNK

Raf

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Aryl Hydrocarbon Receptors

Estrogen Receptor signaling

Estrogen-α

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Non-selective

Estrogen GPER receptors

PPAR

Wnt/Beta-Catenin signaling

β-catenin

Anticancer

Cytotoxic

Anti-oxidant

Mitochondrial complex II

Cyclic nucleotide and related

Adenylyl cyclase (AC)

cAMP

Guanyl cyclase (GC)

Inositol trisphosphate (IP3)

PKA

PKC

Ca²⁺ signaling

Ca²⁺-ATPase (SERCA)

Ca²⁺ binding protein

Ca²⁺-sensitive protease

General compounds

Na⁺/Ca²⁺ exchanger

Mitochondrial permeability transition pore (MPTP)

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G protein

Small monomeric GTPase

G Protein (Heterotrimeric)

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HSP90

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Nitric oxide

Notch

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Stats

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COVID-19 Research

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TMPRSS2

ACE2

Endocytosis

Virus replication, transcription & maturation

RNA Polymerases (RdRP/ RNAP)

Endocytosis / Endosome

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Angiotensin related

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Chemokine Receptors

Cytokine Stimulation/ Production

NF-κB / IκB

Inflammasomes

JAK/STAT

MAPK Signaling

p38 MAPK

MEK

ERK

ERK2 / MAPK1

JNK

Raf

PI3K/Akt/mTOR

Akt

PI3K

mTOR

Protease-Activated Receptors

TLR (Toll-like receptors) signaling

TLR2

TLR7

Organoids

Cell culture reagents & buffers

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Caspase

Inducers

p53

PARP

PARP-1

Non-selective

RIP kinase

Stains

Cell Metabolism

Autophagy

Amyloid-β

Bioactive metabolites

DNA / RNA & protein synthesis

Genome editing / engineering

Oxidative Phosphorylation

Ubiquitin-proteasome system (UPS)

Cytoskeleton and Extracellular Matrix

Actin

Matrix Metalloproteases (MMP)

Microtubule

PI3K/Akt/mTOR

PI3K

ROCK (Rho-kinase)

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Antibiotics

Antimicrobials

Antivirals

COVID-19/SARS-CoV-2 related

Immunosupressants / immunomodulators

Mycotoxin

T-cell Related

Cytokines, chemokines & NF-κB/I-κB

Chemokine Receptors

Cytokine Stimulation/ Production

JNK

NF-κB / IκB

Inflammasome

JAK/STAT

TLR (Toll-like receptors)

TLR2

TLR7

Non-selective

Oxidative Stress

ROS

NOS

Stem cells

Dedifferentiation

Differentiation

iPSCs & ESCs

Mesenchymal Stem cells (MSCs)

Neural Stem Cells (NSCs)

Neurotrophins

Organoids

Proliferation, self-renewal, maintenance

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