Group I (mGlu5, mGlu1)

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Group I metabotropic glutamate receptors (mGlu1, mGlu5) are coupled with phospholipase C (PLC) via Gq proteins; activation causes increased levels of IP3 and diacylglycerol, with intracellullar Ca2+ release and protein kinase C (PKC) activation. Group I receptors are predominantly located post synaptically. Researchers can save 50% on group I metabotropic glutamate receptor agonists, antagonists, positive allosteric modulators (PAMs) and negative allosteric modulators (NAMs) from Hello Bio - they are up to half the price of other suppliers.

Items 1-10 of 19

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  1. Description:

    GABA receptor agonist and glutamatergic modulator

    Pack:
    100mg
    Price:
    $193
    Qty:
  2. CDPPB (HB0175)

    Description:

    Selective mGlu5 positive allosteric modulator

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $108
    Qty:
    Pack:
    50mg
    Price:
    $430
    Qty:
  3. Description:

    Selective mGluR5 agonist. Water soluble sodium salt.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $66
    Qty:
    Pack:
    50mg
    Price:
    $275
    Qty:
  4. (R,S)-CHPG (HB0033)

    Description:

    Selective mGlu5 agonist

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $70
    Qty:
    Pack:
    50mg
    Price:
    $322
    Qty:
  5. CPCCOEt (HB0216)

    Description:

    Selective, non-competitive mGlu1 antagonist

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $105
    Qty:
    Pack:
    50mg
    Price:
    $408
    Qty:
  6. Description:

    mGlu / mGlu5a agonist

    Pack:
    100mg
    Price:
    $80
    Qty:
    Pack:
    250mg
    Price:
    $161
    Qty:
    Pack:
    500mg
    Price:
    $321
    Qty:
    Pack:
    1g
    Price:
    $535
    Qty:
  7. (S)-3,5-DHPG (HB0045)

    3  Reviews
    Top Reviews:
    100% of 100
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    Description:

    Selective group I mGlu receptor agonist. Induces LTD.

    Purity:

    >99%

    Pack:
    1mg
    Price:
    $58
    Qty:
    Pack:
    5mg
    Price:
    $93
    Qty:
    Pack:
    10mg
    Price:
    $166
    Qty:
  8. (R,S)-3,5-DHPG (HB0026)

    Description:

    Selective group I (mGluR1 / mGluR5) agonist

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $92
    Qty:
    Pack:
    50mg
    Price:
    $379
    Qty:
    Pack:
    10mM (add 1ml water)
    Price:
    $31
    Qty:
  9. Fenobam (HB0286)

    1  Review
    Top Reviews:
    80% of 100
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    Description:

    Potent, selective, non-competitive mGlu5 antagonist

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $80
    Qty:
    Pack:
    50mg
    Price:
    $334
    Qty:
  10. Description:

    Novel, inactive photocaged derivative of raseglurant which can be uncaged with violet light. Shows light-dependent analgesic activity in vivo.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $67
    Qty:
    Pack:
    5mg
    Price:
    $302
    Qty:

Items 1-10 of 19

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