Group I (mGlu5, mGlu1)
Group I metabotropic glutamate receptors (mGlu1, mGlu5) are coupled with phospholipase C (PLC) via Gq proteins; activation causes increased levels of IP3 and diacylglycerol, with intracellullar Ca2+ release and protein kinase C (PKC) activation. Group I receptors are predominantly located post synaptically. Researchers can save 50% on group I metabotropic glutamate receptor agonists, antagonists, positive allosteric modulators (PAMs) and negative allosteric modulators (NAMs) from Hello Bio - they are up to half the price of other suppliers.
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Acamprosate calcium (HB0099)Description:
GABA receptor agonist and glutamatergic modulatorPurity:
(R,S)-CHPG sodium salt (HB0034)Description:
Selective mGluR5 agonist. Water soluble sodium salt.Purity:
Competitive, selective group 1 mGlu antagonistPurity: