Group II (mGlu3, mGlu2)

Potent, selective mGlu₂ positive allosteric modulator

Non-selective group I/II mGluR antagonist

Non-selective group I and II mGluR antagonist. Water soluble sodium salt.

Selective mGlu₃ negative allosteric modulator

Selective mGlu₃ agonist, peptide neurotransmitter

Endogenous group II mGlu agonist