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Deuterated Lac-Phe (N-lactoyl-phenylalanine)
IP3 receptor and store-operated channels (SOC) channel antagonist
Aurora B and C kinase inhibitor
Non-selective calcium ionophore
Potent, reversible AMPK activator. Inhibits MSC proliferation.
Potent, cell-permeable calmodulin (CaM) antagonist
Potent, selective Nav1.8 channel inhibitor
Selective TGF-βRI (ALK5), ALK4 and ALK7 inhibitor. Maintains human hiPSC self renewal, 3D growth matrix component and promotes long-term organoid growth. Aids fibroblast to NSC/cardiomyocyte reprogramming.
Potent, selective TRPA1 channel blocker
Selective cPLA2 inhibitor