Enzyme inhibitors and activators...low-cost, high quality
As a specialist supplier of affordable enzyme and signaling pathway research tools, Hello Bio has introduced a range of low cost inhibitors and activators for enzymes such as kinases, phosphatases and more - at prices up to 50% less than other suppliers. Our range includes tools such as ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101.
View our full range of enzyme inhibitors and activators, or browse below:
| ATPase / GTPase Deacetylase Demethylase Esterase |
Kinase
|
Phosphodiesterase Phosphatase Polymerase Protease / Peptidase Synthase Transferase |
Highest quality
Our prices are up to 50% less than other suppliers (view price comparison table). However, we know that product reliability is more important than price. We are based in purpose built labs in the UK and with decades of synthetic and manufacturing chemistry expertise we know what we are doing! For your peace of mind, all of our products are covered by the Hello BioPromise quality guarantee.
Featured enzyme inhibitors and activators
Cmpd101 is a novel, potent and selective G-protein coupled receptor kinase 2 and 3 (GRK2/GRK3) inhibitor (IC50 values are 35, 290 nM and 125 µM at GRK2, GRK3 and GRK5 respectively). It shows little activity at a broad range of other kinases. Membrane permeable, it can be used to study the roles of GRK2/3 in GPCR desensitization and other functions. Find out more…
Protein phosphatase inhibitorsOur growing range includes the potent protein phosphatase inhibitor okadaic acid and the potent calcineurin inhibitor Cyclosporin A
Y-27632 is selective ROCK (Rho-associated protein kinase) inhibitor (Ki values are 0.22 and 0.30 µM at ROCK-I and ROCK-II respectively). Improves culture of a variety of multipotent stem cell types. Inhibits smooth muscle contractility and shows antihypertensive effect. Active in vivo. Read more...
We currently offer the broad spectrum caspase inhibitors: Z-VAD-FMK and Z-VAD-(OMe)-FMK