Histone deacetylase (HDAC)

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Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

Items 1-10 of 19

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  1. AK-7 (HB3747)

    Description:

    Brain-permeable SIRT2 (sirtuin 2) inhibitor

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $409
    Qty:
  2. Apicidin (HB1384)

    Description:

    Potent HDAC inhibitor

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $615
    Qty:
    Pack:
    5mg
    Price:
    $413
    Qty:
  3. CI 994 (HB1385)

    Description:

    Potent, selective HDAC inhibitor

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $126
    Qty:
    Pack:
    50mg
    Price:
    $479
    Qty:
  4. Description:

    Phytotoxin. Derivative of the HDAC inhibitor chlamydocin.

    Purity:

    >95%

    Pack:
    1mg
    Price:
    $225
    Qty:
  5. FK 228 (HB1386)

    Description:

    Potent, selective HDAC1 / HDAC2 inhibitor

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $874
    Qty:
  6. Description:

    Endogenous HDAC1, HDAC3 and HDAC4 inhibitor

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $45
    Qty:
    Pack:
    100mg
    Price:
    $97
    Qty:
  7. Description:

    Endogenous HDAC1, HDAC3 and HDAC4 inhibitor

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $40
    Qty:
    Pack:
    100mg
    Price:
    $90
    Qty:
  8. MC 1568 (HB1390)

    Description:

    Selective class IIa HDAC inhibitor

    Purity:

    >96%

    Pack:
    25mg
    Price:
    $480
    Qty:
  9. MS-275 (HB3983)

    Description:

    HDAC 1 inhibitor

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $257
    Qty:
  10. NSC 3852 (HB1392)

    Description:

    Non-selective HDAC inhibitor

    Pack:
    50mg
    Price:
    $135
    Qty:

Items 1-10 of 19

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