Antagonists & inhibitors

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An antagonist is a drug or chemical that reduces the effect of an agonist. Competitive antagonists bind to the same site on a receptor as the agonist but do not activate it - thereby blocking the action of the agonist. Non-competitive antagonists block the action of the agonist by binding to a different site on the receptor (an allosteric or non-agonist site). A reversible antagonist binds non-covalently and can be washed out. An irreversible antagonist binds covalently and cannot be displaced by either competing ligands or washing. Inhibitors are drugs that can bind to a protein, such as an enzyme and decrease its activity. Researchers can save up to 50% on competitive antagonists, non-competitive antagonists, reversible and irreversible antagonists, and inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. Description:

    LPA1 and LPA2 agonist. Inhibits differentiation of neural stem cells (NSCs) into neurons.

    Pack:
    1mg
    Price:
    $54
    Qty:
    Pack:
    5mg
    Price:
    $165
    Qty:
  2. 2-APB (HB1208)

    Description:

    IP3 receptor and store-operated channels (SOC) channel antagonist

    Pack:
    10mg
    Price:
    $45
    Qty:
    Pack:
    50mg
    Price:
    $148
    Qty:
  3. 7BIO (HB3732)

    Description:

    Aurora B and C kinase inhibitor

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $148
    Qty:
    Pack:
    50mg
    Price:
    $599
    Qty:
  4. Description:

    Potent, cell-permeable calmodulin (CaM) antagonist

    Pack:
    25mg
    Price:
    $278
    Qty:
  5. A 803467 (HB1007)

    Description:

    Potent, selective Nav1.8 channel inhibitor

    Purity:

    >98%

    Pack:
    50mg
    Price:
    $392
    Qty:
  6. A 83-01 (HB3218)

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    Description:

    Selective TGF-βRI (ALK5), ALK4 and ALK7 inhibitor. Maintains human hiPSC self renewal, 3D growth matrix component and promotes long-term organoid growth. Aids fibroblast to NSC/cardiomyocyte reprogramming.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $55
    Qty:
    Pack:
    25mg
    Price:
    $248
    Qty:
  7. A 967079 (HB1156)

    Description:

    Potent, selective TRPA1 channel blocker

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $70
    Qty:
    Pack:
    10mg
    Price:
    $105
    Qty:
    Pack:
    25mg
    Price:
    $234
    Qty:
    Pack:
    50mg
    Price:
    $416
    Qty:
  8. AACOCF3 (HB2354)

    Description:

    Selective cPLA2 inhibitor

    Pack:
    50mg
    Price:
    $467
    Qty:
  9. 17-AAG (HB3599)

    Description:

    Selective Hsp90 inhibitor. Also protects neuroprogenitor cells against apoptosis.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $103
    Qty:
  10. Acetildenafil (HB0103)

    Description:

    Sildenafil analog

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $951
    Qty:

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