Antagonists & inhibitors

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An antagonist is a drug or chemical that reduces the effect of an agonist. Competitive antagonists bind to the same site on a receptor as the agonist but do not activate it - thereby blocking the action of the agonist. Non-competitive antagonists block the action of the agonist by binding to a different site on the receptor (an allosteric or non-agonist site). A reversible antagonist binds non-covalently and can be washed out. An irreversible antagonist binds covalently and cannot be displaced by either competing ligands or washing. Inhibitors are drugs that can bind to a protein, such as an enzyme and decrease its activity. Researchers can save up to 50% on competitive antagonists, non-competitive antagonists, reversible and irreversible antagonists, and inhibitors from Hello Bio - they are up to half the price of other suppliers.

Items 1-10 of 699

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  1. 2-APB (HB1208)

    1  Review
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    Description:

    IP3 receptor and store-operated channels (SOC) channel antagonist

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $53
    Qty:
    Pack:
    50mg
    Price:
    $174
    Qty:
  2. 7BIO (HB3732)

    Description:

    Aurora B and C kinase inhibitor

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $174
    Qty:
    Pack:
    50mg
    Price:
    $704
    Qty:
  3. Description:

    Potent, cell-permeable calmodulin (CaM) antagonist

    Pack:
    25mg
    Price:
    $326
    Qty:
  4. A 803467 (HB1007)

    Description:

    Potent, selective Nav1.8 channel inhibitor

    Purity:

    >98%

    Pack:
    50mg
    Price:
    $460
    Qty:
  5. A 83-01 (HB3218)

    1  Review
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    Description:

    Selective TGF-βRI (ALK5), ALK4 and ALK7 inhibitor. Maintains human hiPSC self renewal, 3D growth matrix component and promotes long-term organoid growth. Aids fibroblast to NSC/cardiomyocyte reprogramming.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $80
    Qty:
    Pack:
    25mg
    Price:
    $270
    Qty:
  6. A 967079 (HB1156)

    Description:

    Potent, selective TRPA1 channel blocker

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $82
    Qty:
    Pack:
    10mg
    Price:
    $123
    Qty:
    Pack:
    25mg
    Price:
    $275
    Qty:
    Pack:
    50mg
    Price:
    $489
    Qty:
  7. AACOCF3 (HB2354)

    Description:

    Selective cPLA2 inhibitor

    Pack:
    50mg
    Price:
    $549
    Qty:
  8. 17-AAG (HB3599)

    Description:

    Selective Hsp90 inhibitor. Also protects neuroprogenitor cells against apoptosis.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $121
    Qty:
  9. Acetildenafil (HB0103)

    Description:

    Sildenafil analog

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $1,118
    Qty:
  10. Actinomycin D (HB1477)

    Description:

    RNA polymerase inhibitor. Apoptosis inducer.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $113
    Qty:
    Pack:
    5mg
    Price:
    $61
    Qty:
    Pack:
    100mg
    Price:
    $804
    Qty:
    Pack:
    25mg
    Price:
    $211
    Qty:

Items 1-10 of 699

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