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Selective TGF-βRI (ALK5), ALK4 and ALK7 inhibitor. Maintains human hiPSC self renewal, 3D growth matrix component and promotes long-term organoid growth. Aids fibroblast to NSC/cardiomyocyte reprogramming.
Selective EGF receptor tyrosine kinase inhibitor
Member of the neurotrophin growth factor family. Plays an important role in synaptic plasticity and neurogenesis.
Potent, selective colony stimulating factor 1 receptor (CSF-1R) inhibitor
TGF-βRI and CK1 inhibitor
Protein kinase inhibitor
TGF-β signaling inhibitor
Selective ALK2 inhibitor. Promotes iPSC neurogenesis.
Toll-like receptor 2 (TLR2) and TLR6 agonist
Selective toll-like receptor 7 (TLR7) agonist