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PPT

(HB2499)
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Product overview

Name PPT
Purity >98%
Description Selective ERα estrogen receptor agonist
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (3) Frequently bought together
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Biological Data

Biological description Selective ERα estrogen receptor agonist (Kd values are 2 and 1000 nM at ERα and ERβ respectively). Displays a 410-fold higher selectivity for ERα over ERβ. Shows neuroprotective effects. Active in vivo.

Solubility & Handling

Solubility overview Soluble in DMSO (100 mM)
Storage instructions +4°C
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >98%
Chemical name 4,4',4''-(4-Propyl-[1H]-pyrazole-1,3,5-triyl)trisphenol
Molecular Weight 386.45
Chemical structure PPT [263717-53-9] Chemical Structure
Molecular Formula C24H22N2O3
CAS Number 263717-53-9
PubChem identifier 6095481
SMILES CCCC1=C(N(NC1=C2C=CC(=O)C=C2)C3=CC=C(C=C3)O)C4=CC=C(C=C4)O
InChi InChI=1S/C24H22N2O3/c1-2-3-22-23(16-4-10-19(27)11-5-16)25-26(18-8-14-21(29)15-9-18)24(22)17-6-12-20(28)13-7-17/h4-15,25,28-29H,2-3H2,1H3
InChiKey UOSWGERPQQOSHS-UHFFFAOYSA-N
MDL number MFCD03453628

References for PPT

References are publications that support the biological activity of the product

  • Pharmacokinetics of the estrogen receptor subtype-selective ligands, PPT and DPN: quantification using UPLC-ES/MS/MS.

    Sepehr E et al (2012) J Pharm Biomed Anal 71 : 119-26.
    Read more (PubMedID: 22981216)

  • The possible role of estrogen and selective estrogen receptor modulators in a rat model of Parkinson's disease.

    Baraka AM et al (2011) Life Sci 88(19-20) : 879-85.
    Read more (PubMedID: 21420980)

  • Estrogen receptor subtypes alpha and beta contribute to neuroprotection and increased Bcl-2 expression in primary hippocampal neurons.

    Zhao L et al (2004) Brain Res 1010(1-2) : 22-34.
    Read more (PubMedID: 15126114)

3 Item(s)

Grouped product items
Order: HB2499
Pack PriceQty
5mg
$100
10mg
$195
25mg
$400
Selective ERα estrogen receptor agonist
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

Shipping will be calculated at checkout

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