Two-P
The Two-P (K2P) potassium channels are a family of 15 members (e.g. TREK1, TASK3), are responsible for background potassium currents and are important in stabilizing membrane potential. Researchers can save up to 50% on Two-P (K2P) potassium channel blockers and activators e.g. ML 335, ML 336, CAT335 and ML 402 from Hello Bio - they are around half the price of other suppliers.
CAT335 (HB8146)
Description:K2P2.1 (TREK-1) modulator. Used with ML336 as part of the CATKLAMP chemogenetic strategy. Selectively and irreversibly activates TREK-1CG* but not wild-type K2P2.1 (TREK-1)
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Purity:>98%
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ML 336 (K2P2.1/ TREK-1 modulator) (HB7386)
Description:Covalent K2P2.1 (TREK-1) modulator. Used with CAT335 as part of the CATKLAMP chemogenetic strategy.
Purity:>99%
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Riluzole (HB6093)
Description:Na+ channel blocker / glutamate inhibitor. TREK-1 K2P channel activator.
Purity:>98%
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Riluzole hydrochloride (HB0548)
Description:Na+ channel blocker / glutamate inhibitor. TREK-1 K2P channel activator. Water soluble.
Purity:>98%
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Spadin (HB5438)
Description:Potent TREK-1/ K2P2.1 channel blocker. Shows fast-acting antidepressant effects.
