Ligand-gated ion channel
Ligand-gated ion channels (also known as ionotropic receptors) are transmembrane ion channel proteins that allow passage of ions upon activation by a specific chemical. Ligand-gated ion channels include ionotropic glutamate receptors (AMPA, kainate and NMDA receptors), GABAA, GABAA-ρ, Glycine, 5-HT3, HCN, acetylcholine nicotinic and purinergic (P2X) receptors. Commonly used ligands include D-AP5, NBQX, kainic acid, and gabazine. Researchers can save up to 50% on ligand-gated ion channel (ionotropic receptor) agonists, antagonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.
View products: Ionotropic glutamate | ACh Nicotinic | AMPA | GABAA | Glycine | 5-HT3 | Kainate | NMDA | P2X | Neuroscience Research Tools
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UBP 302 (HB0627)
Description:Potent, selective GluK1 subunit selective kainate receptor antagonist
Purity:>98%
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UBP 310 (HB0628)
Description:Potent, selective GluK1 / GluK3 subunit selective kainate receptor antagonist
Purity:>98%
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UBP709 (HB9204)
Description:NMDAR pan-PAM that potentiates all GluN2 subunits. Enhances LTD and decreases LTP.
Purity:>98%
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UBP714 ammonium salt (HB8161)
Description:NMDAR PAM which potentiates GluN2A and GluN2B with minimal effects on 2C and 2D.
Purity:>98%
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uPSEM792 hydrochloride (HB8542)
Description:Ultrapotent PSEM agonist for PSAM4-GlyR and PSAM4-5HT3. Brain penetrant.
Purity:>99%
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uPSEM817 tartrate (HB8620)
Description:Selective, ultrapotent PSEM agonist for PSAM4-GlyR and PSAM4-5HT3. Brain penetrant.
Purity:>99%
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Varenicline tartrate (HB2070)
Description:Selective α4β2 nAChR partial agonist; orally active
Purity:>99%
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