Potent and selective GluK1 (formerly GluR5) subunit selective kainate receptor antagonist (apparent KD = 402 nM). Active enantiomer of UBP 296. Shows anxiolytic effects.
Solubility & Handling
Solubility overview
Soluble in NaOH(aq) (25mM, gentle warming) or DMSO (20mM, gentle warming)
Storage instructions
Room temperature
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
References are publications that support the biological activity of the product
Presynaptic facilitation of glutamate release in the basolateral amygdala: a mechanism for the anxiogenic and seizurogenic function of GluK1 receptors.
Aroniadou-Anderjaska V et al (2012) Neuroscience 221 : 157-69.
![UBP 302 [745055-91-8] Chemical Structure](https://cdn.hellobio.com/media/catalog/product//h/b/hb0627.png "UBP 302 [745055-91-8]")
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