The store will not work correctly in the case when cookies are disabled.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
Images UBP 302 product vial image | Hello Bio
UBP 302 product vial image | Hello Bio Biological Data Biological description Potent and selective GluK1 (formerly GluR5) subunit selective kainate receptor antagonist (apparent KD = 402 nM). Active enantiomer of UBP 296. Shows anxiolytic effects.
Solubility & Handling Storage instructions Room temperature
Solubility overview Soluble in NaOH(aq) (25mM, gentle warming) or DMSO (20mM, gentle warming)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Chemical Data Chemical name (S )-1-(2-Amino-2-carboxyethyl)-3-(2-carboxybenzyl)pyrimidine-2,4-dione
Chemical structure
Molecular Formula C15 H15 N3 O6
PubChem identifier 6420161
SMILES O=C(C=CN(C[C@H](N)C(O)=O)C2=O)N2CC1=CC=CC=C1C(O)=O
InChiKey UUIYULWYHDSXHL-NSHDSACASA-N
References for UBP 302 References are publications that support the biological activity of the product
Presynaptic facilitation of glutamate release in the basolateral amygdala: a mechanism for the anxiogenic and seizurogenic function of GluK1 receptors. Aroniadou-Anderjaska V et al (2012) Neuroscience 221 : 157-69. Synthesis and pharmacology of willardiine derivatives acting as antagonists of kainate receptors. Dolman NP et al (2005) J Med Chem 48(24) : 7867-81. Characterisation of UBP296: a novel, potent and selective kainate receptor antagonist. More JC et al (2004) Neuropharmacology 47(1) : 46-64.
Potent, selective GluK1 subunit selective kainate receptor antagonist
![UBP 302 [745055-91-8] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb0627.png "UBP 302 [745055-91-8]")
Understanding purity and quality - a guide for life scientists
