Amino acid analog of Glutamine. Also binds to NMDA glycine, kainate and AMPA receptors (IC50 vales are 347, 41.5 and 24.6 µM respectively). Blood brain barrier permeable and down regulates COX-2 expression. Displays antioxidant and neuroprotective properties. Also promotes hESC self-renewal.
Solubility & Handling
Storage instructions
Room temperature
Solubility overview
Soluble in water (100mM)
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Y-27632 is a selective ROCK inhibitor. Frequently used 3D growth matrix component and for production of organoids. Also used when inducing neurons from fibroblasts. Manufactured to a high degree of optical purity.