My Cart
My account
Menu
Main Menu

Tramiprosate

(HB0866)
Be the first to add a publication
Technical documents: CoA Datasheet
Be the first to review this product
Add to Wish List

Product overview

Name Tramiprosate
Alternative names Homotaurine
Description GABA analogue / sGAG mimetic
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (3)
Write Your Own Review
You're reviewing:Tramiprosate
Rate this item:

Biological Data

Biological description GABA analogue and sulfated glycosaminoglycan (sGAG) mimetic. Shows protective actions against kainic acid convulsive and cytotoxic effects. Blocks PSD95 - nNOS interaction to show neuroprotective effects against ischemic stroke. Also decreases Amyloid-β plaques in Alzheimer's models. Blood-brain barrier permeable.

Solubility & Handling

Storage instructions +4°C
Solubility overview Soluble in water (100mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

=
x
x
More Info

Dilution

x
=
x
More Info

Chemical Data

Chemical name 3-Amino-1-propanesulfonic acid
Molecular Weight 139.17
Chemical structure Tramiprosate [3687-18-1] Chemical Structure
Molecular Formula C3H9NO3S
CAS Number 3687-18-1
PubChem identifier 1646
SMILES NCCCS(=O)(O)=O
InChiKey SNKZJIOFVMKAOJ-UHFFFAOYSA-N

References for Tramiprosate

References are publications that support the biological activity of the product

  • Tramiprosate protects neurons against ischemic stroke by disrupting the interaction between PSD95 and nNOS.

    Wu S et al (2014) Neuropharmacology 83 : 107-17.
    Read more (PubMedID: 24769446)

  • Targeting soluble Abeta peptide with Tramiprosate for the treatment of brain amyloidosis.

    Gervais F et al (2007) Neurobiol Aging 28(4) : 537-47.
    Read more (PubMedID: 16675063)

  • Homotaurine (3 aminopropanesulfonic acid; 3APS) protects from the convulsant and cytotoxic effect of systemically administered kainic acid.

    Fariello RG et al (1982) Neurology 32(3) : 241-5.
    Read more (PubMedID: 7199633)

3 Item(s)

Related Products
Grouped product items
Order: HB0866
Pack PriceQty
1g
$41
GABA analogue / sGAG mimetic
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

Shipping will be calculated at checkout

Contact Us

Call 609-683-7500
Fax 609-228-4994

customercare-usa@hellobio.com

New Products in this Area

Pexidartinib (PLX3397)
HB8991

Potent CSF-1R inhibitor. Widely used microglia-depletion agent.

Related Products

(-)-Bicuculline methochloride
Code:
HB0895
Pack:
25mg, 50mg, 125mg
Price:
$191, $373, $686
Prototypic, competitive GABAA receptor antagonist
SR 95531 hydrobromide (Gabazine)
Code:
HB0901
Pack:
10mg, 50mg, 10mM (add 1ml water)
Price:
$102, $393, $66
(Free trial)
Selective, competitive GABAA receptor antagonist
Picrotoxin
Code:
HB0506
Pack:
1g, 5x1g
Price:
$45, $193
Non-competitive GABAA receptor antagonist