Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. Description:

    Nicotinic acetylcholine receptors (nACHR) antagonist. Neuromuscular blocker.

    Purity:

    >98%

    Pack:
    50mg
    Price:
    $55
    Qty:
  2. Pack:
    1mg
    Price:
    $53
    Qty:
    Pack:
    5mg
    Price:
    $130
    Qty:
    Pack:
    10mg
    Price:
    $149
    Qty:
    Pack:
    50mg
    Price:
    $627
    Qty:
  3. Description:

    Antibody to tyrosine hydroxylase (TH) - the rate limiting enzyme in catecholamine synthesis and used as a marker for catecholaminergic (dopaminergic and noradrenergic) neurones in the CNS. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Rabbit
    Clonality: Polyclonal
    Reactivity Tested: Mouse, Rat
    Pack:
    25μg
    Price:
    $179
    Qty:
    Pack:
    100μL
    Price:
    $536
    Qty:
  4. Description:

    Antibody to tyrosine hydroxylase (TH) - the rate limiting enzyme in catecholamine synthesis and used as a marker for catecholaminergic (dopaminergic and noradrenergic) neurones in the CNS. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Chicken
    Clonality: Polyclonal
    Reactivity Tested: Mouse, Rat
    Pack:
    25μg
    Price:
    $91
    Qty:
    Pack:
    100μg
    Price:
    $272
    Qty:
  5. Description:

    Antibody to tyrosine hydroxylase (TH) - the rate limiting enzyme in catecholamine synthesis and used as a marker for catecholaminergic (dopaminergic and noradrenergic) neurones in the CNS. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse, Rat
    Pack:
    25μg
    Price:
    $143
    Qty:
    Pack:
    100μg
    Price:
    $430
    Qty:
  6. Pack:
    1mg
    Price:
    Qty:
    Pack:
    5mg
    Price:
    $171
    Qty:
    Pack:
    25mg
    Price:
    $708
    Qty:
  7. UBP145 (HB4717)

    Description:

    Selective antagonist for GluN2D subunit containing NMDA receptors

    Purity:

    >97%

    Pack:
    10mg
    Price:
    $172
    Qty:
  8. Pack:
    10mg
    Price:
    $305
    Qty:
    Pack:
    50mg
    Price:
    $1,375
    Qty:
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