Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. Go 6983 (HB0303)

    Description:

    Broad spectrum PKC inhibitor. Optimizes naïve human pluripotent stem cell growth and viability

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $34
    Qty:
    Pack:
    5mg
    Price:
    $160
    Qty:
    Pack:
    10mg
    Price:
    $240
    Qty:
  2. Pack:
    100mg
    Price:
    $140
    Qty:
    Pack:
    250mg
    Price:
    $278
    Qty:
    Pack:
    500mg
    Price:
    $410
    Qty:
  3. Gramine (HB0305)

    Description:

    5-HT2A receptor antagonist

    Purity:

    >99%

    Pack:
    100mg
    Price:
    $474
    Qty:
  4. GSK 429286 (HB2290)

    Description:

    Selective ROCK inhibitor

    Purity:

    >97%

    Pack:
    10mg
    Price:
    $278
    Qty:
  5. GSK'872 (HB5933)

    Description:

    Potent, selective RIP3 inhibitor. Necroptosis inhibitor.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $139
    Free trial
    Qty:
    Pack:
    50mg
    Price:
    $584
    Qty:
    Pack:
    10mM solution (in 1mL DMSO)
    Price:
    $91
    Qty:
  6. Pack:
    10mg
    Price:
    $292
    Qty:
    Pack:
    50mg
    Price:
    $978
    Qty:
  7. Pack:
    10mg
    Price:
    $285
    Qty:
    Pack:
    50mg
    Price:
    $1,108
    Qty:
  8. GsMTx4 (HB1161)

    Description:

    Piezo and TRP mechanosensitive channels inhibitor

    Purity:

    >95%

    Pack:
    100μg
    Price:
    $282
    Qty:
  9. Description:

    Antibody to the GST tag - widely used as a protein tag in molecular biology. Part of the ValidAb™ range of highly validated, data-rich antibodies. 

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Species Independent
    Pack:
    25μg
    Price:
    $145
    Qty:
    Pack:
    100μg
    Price:
    $324
    Qty:
  10. GV-58 (HB3920)

    Description:

    Selective N- and P/Q-type Ca2+-channel agonist

    Purity:

    >97%

    Pack:
    5mg
    Price:
    $313
    Qty:
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