Product overview

Name GSK 429286
Alternative names GSK429286A
Purity >97%
Description Selective ROCK inhibitor
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Biological Data

Biological description Selective ROCK (Rho-kinase) inhibitor (IC50 values are 14, 780 and 1940 nM for ROCK1, RSK and p70S6K respectively).

Solubility & Handling

Storage instructions +4°C
Solubility overview Soluble in DMSO (100mM) or ethanol (25mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Purity >97%
Chemical name 4-[4-(Trifluoromethyl)phenyl]-N-(6- Fluoro-1H-indazol-5-yl)-2-methyl-6-oxo-1,4,5,6-tet rahydro-3-pyridinecarboxamide
Molecular Weight 432.37
Molecular Formula C21H16F4N4O2
CAS Number 864082-47-3
PubChem identifier 11373846
SMILES O=C1CC(C2=CC=C(C(F)(F)F)C=C2)C(C(NC3=C(F)C=C(NN=C4)C4=C3)=O)=C(C)N1
InChiKey OLIIUAHHAZEXEX-UHFFFAOYSA-N