Product overview

Name Gossypol
Purity >90%
Description Dehydrogenase enzyme inhibitor
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Biological Data

Biological description Dehydrogenase enzyme inhibitor. Bcl-2 homology 3 (BH3)-mimetic agent, binds to the BH3 domain of members of the B-cell lymphoma 2 (Bcl-2) family. Inhibits APE-1 (apurinic/apyrimidinic endonuclease 1) activity. Shows antioxidant, antiviral, antiparasitic, apoptotic and anticancer actions.

Solubility & Handling

Solubility overview Soluble in ethanol (25mg/ml) or DMF (25mg/ml)
Storage instructions -20°C
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Purity >90%
Chemical name Pogosin; AT101
Molecular Weight 518.56
Chemical structure Gossypol  [303-45-7] Chemical Structure
Molecular Formula C30H30O8
CAS Number 303-45-7
PubChem identifier 3503
SMILES CC1=C(C(=C2C(=C1)C(=C(C(=C2C=O)O)O)C(C)C)O)C3=C(C=C4C(=C3O)C(=C(C(=C4C(C)C)O)O)C=O)C
Source Synthetic
InChiKey QBKSWRVVCFFDOT-UHFFFAOYSA-N

References for Gossypol

References are publications that support the biological activity of the product

4 Item(s)