Histone deacetylase (HDAC)
Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.
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GYKI 52466 hydrochloride (HB0311)
Description:Selective, non-competitive AMPA receptor antagonist
Purity:>98%
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GYKI 53655 hydrochloride (HB0312)
Description:Non-competitive AMPA receptor antagonist. Also blocks kainate GluK3 homomeric receptors.
Purity:>98%
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Anti-Histone H3 antibody ValidAbâ„¢ (HB6980)
Description:Antibody to Histone H3 - Histone protein used as a loading control for western blotting. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: RabbitClonality: PolyclonalReactivity Tested: Mouse, Rat -
H 89 dihydrochloride (HB0314)
Description:Potent, non-selective kinase inhibitor.Also improves dissociate hESCs survival and clonogenicity.
Purity:>99%
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HA 1100 hydrochloride (HB2293)
Description:Selective, reversible, cell-permeable ROCK inhibitor
Purity:>99%
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Haloperidol hydrochloride (HB1842)
Description:Dopamine receptor antagonist with partial D2-like selectivity
Purity:>99%
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