Potent and selective histone demethylase KDM6 subfamily inhibitor, selective for JMJD3 and UTX (IC50 = 60 nM for human JMJD3). Reduces macrophage proinflammatory cytokine production.
Solubility & Handling
Solubility overview
Soluble in DMSO (100mM) or ethanol (100mM)
Storage instructions
room temperature (desiccate)
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
![GSK J1 [1373422-53-7] Chemical Structure](https://cdn.hellobio.com/media/catalog/product//h/b/hb1405.png "GSK J1 [1373422-53-7]")
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