Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. Gardiquimod (HB3915)

    Description:

    Selective toll-like receptor 7 (TLR7) agonist

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $258
    Qty:
  2. Pack:
    250μg
    Price:
    $103
    Free trial
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    Pack:
    1mg
    Price:
    $276
    Qty:
  3. 1  Review
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    Description:

    Antibody to GAT1 - GABA reuptake transporter and marker for GABAergic interneurones. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Rabbit
    Clonality: Polyclonal
    Reactivity Tested: Mouse, Rat
    Pack:
    25μL
    Price:
    $179
    Qty:
    Pack:
    100μL
    Price:
    $536
    Qty:
  4. Gatifloxacin (HB3263)

    Description:

    Antibiotic; bacterial type II topoisomerase inhibitor. Activates ESC short term renewal.

    Purity:

    >98%

    Pack:
    250mg
    Price:
    $128
    Qty:
    Pack:
    1g
    Price:
    $437
    Qty:
  5. Pack:
    10mg
    Price:
    $107
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    Pack:
    50mg
    Price:
    $367
    Qty:
  6. Genistein (HB2775)

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    Description:

    Protein tyrosine kinase inhibitor and PPARγ agonist. Phytoestrogen.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $36
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    Pack:
    50mg
    Price:
    $141
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  7. Geodin (HB3918)

    Description:

    Plasminogen activator (PAI-1) inhibitor

    Purity:

    >95%

    Pack:
    5mg
    Price:
    $540
    Qty:
  8. Description:

    Antibody to GFAP - cytoskeletal protein used as an astrocyte marker. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse, Rat
    Pack:
    25μg
    Price:
    $144
    Qty:
    Pack:
    100μg
    Price:
    $325
    Qty:
  9. Description:

    Antibody to GFAP - cytoskeletal protein used as an astrocyte marker. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Chicken
    Clonality: Polyclonal
    Reactivity Tested: Mouse, Rat
    Pack:
    25μL
    Price:
    $164
    Qty:
    Pack:
    100μL
    Price:
    $366
    Qty:
  10. Description:

    Antibody to GFAP - cytoskeletal protein used as an astrocyte marker. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Rabbit
    Clonality: Polyclonal
    Reactivity Tested: Mouse, Rat
    Pack:
    100μL
    Price:
    $371
    Qty:
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