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Haloperidol hydrochloride

(HB1842)
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Product overview

Name Haloperidol hydrochloride
Alternative names Haloperidol hydrochloride
Purity >99%
Description Dopamine receptor antagonist with partial D2-like selectivity
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (4) Frequently bought together
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Biological Data

Biological description

Dopamine receptor antagonist with partial D2-like receptor selectivity (Ki values are 0.53, 2.7, 2.3, 27 and 48 nM at D2, D3, D4, D1 and D5 receptors respectively).

Shows variety of biological actions. Active in vivo.

Recently investigated as part of COVID-19 compound repurposing.

Solubility & Handling

Storage instructions Room temperature
Solubility overview

Soluble in DMSO (20 mM with warming), and in ethanol (10 mM with warming)

Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >99%
Chemical name 4-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)-1-butanone hydrochloride
Molecular Weight 412.33
Chemical structure Haloperidol hydrochloride [1511-16-6] Chemical Structure
Molecular Formula C21H23ClFNO2.HCl
CAS Number 1511-16-6
PubChem identifier 11495267
SMILES Cl.OC1(CCN(CCCC(=O)C2=CC=C(F)C=C2)CC1)C1=CC=C(Cl)C=C1
InChiKey JMRYYMBDXNZQMH-UHFFFAOYSA-N

References for Haloperidol hydrochloride

References are publications that support the biological activity of the product

  • A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

    Krogan et al (2020) Nature 7816 : 459-468
    Read more (PubMedID: 32353859)

  • Antipsychotic drugs: importance of dopamine receptors for mechanisms of therapeutic actions and side effects.

    Strange PG (2001) Pharmacol Rev 53(1) : 119-33.
    Read more (PubMedID: 11171942)

  • Inhibition of N-methyl-D-aspartate receptors by haloperidol: developmental and pharmacological characterization in native and recombinant receptors.

    Lynch DR et al (1996) J Pharmacol Exp Ther 279(1) : 154-61.
    Read more (PubMedID: 8858988)

  • Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1.

    Sunahara RK et al (1991) Nature 350(6319) : 614-9.
    Read more (PubMedID: 1826762)

4 Item(s)

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Order: HB1842
Pack PriceQty
100mg
$87
Dopamine receptor antagonist with partial D2-like selectivity
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Standard: $35

Hazardous: $35

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