Product overview
| Name | HA 1100 hydrochloride |
| Description | Selective, reversible, cell-permeable ROCK inhibitor |
| Alternative names | Hydroxyfasudil |
| Purity | >99% |
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Biological Data
| Biological description | Selective, reversible, ATP-competitive ROCK inhibitor. Cell-permeable. Active metabolite of Fasudile (HA-1077). Displays ~ 100-fold selective over other protein kinases. Shows potent vasodilatory effects. Active in vivo. |
Solubility & Handling
| Storage instructions | -20°C |
| Solubility overview | Soluble in water (20mM) |
| Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
| Purity | >99% |
| Chemical name | 1-[(1,2-Dihydro-1-oxo-5-isoquinolin yl)sulfonyl]hexahydro-1H-1,4-diazepine hydrochloride |
| Molecular Weight | 343.83 |
| Molecular Formula | C14H17N3O3S.HCl |
| CAS Number | 155558-32-0 |
| PubChem identifier | 11371328 |
| SMILES | Cl.OC1=NC=CC2=C(C=CC=C12)S(=O)(=O)N1CCCNCC1 |
| InChiKey | XWWFOUVDVJGNNG-UHFFFAOYSA-N |
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