Product overview

Name HA 1100 hydrochloride
Alternative names Hydroxyfasudil
Purity >99%
Description Selective, reversible, cell-permeable ROCK inhibitor
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Biological Data

Biological description Selective, reversible, ATP-competitive ROCK inhibitor. Cell-permeable. Active metabolite of Fasudile (HA-1077). Displays ~ 100-fold selective over other protein kinases. Shows potent vasodilatory effects. Active in vivo.

Solubility & Handling

Storage instructions -20°C
Solubility overview Soluble in water (20mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Chemical Data

Purity >99%
Chemical name 1-[(1,2-Dihydro-1-oxo-5-isoquinolin yl)sulfonyl]hexahydro-1H-1,4-diazepine hydrochloride
Molecular Weight 343.83
Molecular Formula C14H17N3O3S.HCl
CAS Number 155558-32-0
PubChem identifier 11371328
SMILES Cl.OC1=NC=CC2=C(C=CC=C12)S(=O)(=O)N1CCCNCC1
InChiKey XWWFOUVDVJGNNG-UHFFFAOYSA-N