Potent, non-selective kinase inhibitor. Protein kinase A inhibitor (IC50 = 135 nM). Also inhibits S6K1, MSK1, ROCKII, PKBα and MAPKAP-Klb (IC50 values are 80, 120 and 270 nM, 2.6 µM and 2.8 µM respectively). Also improves dissociate hESCs survival and clonogenicity.
Solubility & Handling
Storage instructions
-20°C
Solubility overview
Soluble in water (25mM) or DMSO (100mM)
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Y-27632 is a selective ROCK inhibitor. Frequently used 3D growth matrix component and for production of organoids. Also used when inducing neurons from fibroblasts. Manufactured to a high degree of optical purity.
![H 89 dihydrochloride [130964-39-5] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb0314.png "H 89 dihydrochloride [130964-39-5]")
Understanding purity and quality - a guide for life scientists
