Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. Pack:
    25mg
    Price:
    $140
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  2. Description:

    L-type Ca2+ channel agonist. Aids iPSCs generation from Mouse embryonic fibroblasts.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $130
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    Pack:
    50mg
    Price:
    $539
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  3. Pack:
    5mg
    Price:
    $99
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    Pack:
    10mg
    Price:
    $143
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    Pack:
    50mg
    Price:
    $571
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  4. Description:

    Member of the neurotrophin growth factor family. Plays an important role in synaptic plasticity and neurogenesis.

    Pack:
    2μg
    Price:
    $68
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    Pack:
    10μg
    Price:
    $271
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  5. BDS II (HB1242)

    Description:

    Selective, reversible Kv3 channel inhibitor

    Pack:
    100μg
    Price:
    $950
    Qty:
  6. Becatecarin (HB3796)

    Description:

    Topoisomerase II inhibitor

    Purity:

    >98%

    Pack:
    250μg
    Price:
    $221
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    Pack:
    1mg
    Price:
    $649
    Qty:
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    Description:

    Antibody to βIII Tubulin - cytoskeletal protein used as a neuronal marker. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse, Rat
    Pack:
    25μg
    Price:
    $136
    Qty:
    Pack:
    100μg
    Price:
    $311
    Qty:
  8. Description:

    Antibody to β-tubulin - cytoskeletal component widely used for imaging microtubules and as a loading control. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse, Rat, Human
    Pack:
    25μg
    Price:
    $140
    Qty:
    Pack:
    100μg
    Price:
    $311
    Qty:
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