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Biological Data
| Biological description | Protein tyrosine phosphatase 1B (PTB1B) inhibitor (IC50 = 20.8 µM). Inhibits mitochondrial lipid peroxidation. Shows antibacterial, antioxidant and antitumor actions. |
Solubility & Handling
| Solubility overview | Soluble in DMSO or ethanol |
| Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
| Chemical name | 4-(3-Ethenyl-3,7-dimethyl-1,6-octadienyl)phenol |
| Chemical structure | ![Bakuchiol [10309-37-2] Chemical Structure](data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR4nGP6zwAAAgcBApocMXEAAAAASUVORK5CYII= "Bakuchiol [10309-37-2]") |
| Molecular Formula | C18H24O |
| PubChem identifier | 5468522 |
| SMILES | CC(=CCCC(C)(C=C)C=CC1=CC=C(C=C1)O)C |
References for Bakuchiol
References are publications that support the biological activity of the product
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Anti-tumor effects of bakuchiol, an analogue of resveratrol, on human lung adenocarcinoma A549 cell line.
Chen Z et al (2010) Eur J Pharmacol 643(2-3) : 170-9. -
Bakuchiol, an antibacterial component of Psoralidium tenuiflorum.
Hsu PJ et al (2009) Nat Prod Res 23(8) : 781-8. -
In vitro protein tyrosine phosphatase 1B inhibitory phenols from the seeds of Psoralea corylifolia.
Kim YC et al (2005) Planta Med 71(1) : 87-9. -
Inhibition of mitochondrial lipid peroxidation by Bakuchiol, a meroterpene from Psoralea corylifolia.
Haraguchi H et al (2000) Planta Med 66(6) : 569-71.
![Bakuchiol [10309-37-2] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb0129.png "Bakuchiol [10309-37-2]")
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