Cell permeable Ca2+ chelator. Hydrolysed by cytosolic esterases. Useful for manipulation of cellular Ca2+ levels. Open channel blocker of Kv channels (IC50 values are 1.3, 1.45 and 1.23 µM for Kv 11.1, hKv 1.3 and hKv 1.5 channels respectively). BAPTA analog. For optimal cell loading, F-127 is available either as a 10% solution in water (HB16503) and 20% solution in DMSO (HB9631).
Solubility & Handling
Storage instructions
-20°C
Solubility overview
Soluble in DMSO (30mM)
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.