Cell permeable Ca2+ chelator. Hydrolysed by cytosolic esterases. Useful for manipulation of cellular Ca2+ levels. Open channel blocker of Kv channels (IC50 values are 1.3, 1.45 and 1.23 µM for Kv 11.1, hKv 1.3 and hKv 1.5 channels respectively). BAPTA analog. For optimal cell loading, F-127 is available either as a 10% solution in water (HB16503) and 20% solution in DMSO (HB9631).
Solubility & Handling
Solubility overview
Soluble in DMSO (30mM)
Storage instructions
-20°C
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.