Selective and reversible Kv3 channel inhibitor. Found in the venom of the sea anemone Anemonia sulcata. Shows higher selectivity for Kv3.4 (IC50 = 56 nM). Also antagonist at receptor site 3 of voltage-gated sodium channels (IC50 = 5.2 µM). Displays antihypertensive and antiviral properties.
Solubility & Handling
Storage buffer
soluble in any aqueous buffer
Storage instructions
-20°C
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Understanding purity and quality - a guide for life scientists