L-type Ca2+ channel agonist. Causes reduced inotropy in the myocardium. Also aids induced pluripotent stem cell generation from mouse embryonic fibroblasts (MEFs). Shows convulsive and vasoconstrictive actions.
Solubility & Handling
Soluble in ethanol (100mM)
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Activation of protein kinase C by 1,4-dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)-phenyl]-3-py rid ine carboxylic acid methyl ester (Bay K 8644), a calcium channel agonist, in alveolar type II cells.
Sen N et al (1997) Biochem Pharmacol 53(9) : 1307-13.