Stem cells
Small molecule pharmacological tools can be used to manipulate signalling pathways during the in vitro culture of stem cells. These small molecules can be used to target signaling pathways that control cell proliferation and differentiation. Researchers can save up to 50% on high purity stem cell research tools such as ROCK inhibitor Y 27632, A83-01 and CHIR 99021 from Hello Bio - they are around half the price of other suppliers.
View products:  Differentiation | Organoids | Proliferation/Self-renewal | Reprogramming | Stem Cell Signaling View resources: Stem Cell Research Tools & Mini-Reviews
Recombinant human GDNF protein (HB5735)
Description:Neurotrophin which enhances differentiation and survival of dopaminergic neurons
Recombinant human NT-3 protein (HB8373)
Description:Neurotrophin involved in neuron development, survival and differentiation
SAG (HB3107)
Description:Cell permeable Sonic hedgehog (Shh) agonist and Smo agonist. Enhances neuronal differentiation of iPSC into dopaminergic neurons.
Purity:>98%
SB 431542 (HB3555)
Description:Potent, selective TGF-βRI ALK5, ALK4, ALK7 inhibitor. Induces sheet formation, proliferation, differentiation of ESC-derived endothelial cells and replaces SOX2 in reprogramming protocols.3D growth matrix component and can be used in production of organoids.
Purity:>98%
SU 5402 (HB3133)
Description:Potent FGFR and VEGFR inhibitor. Attenuates integrin β4-induced neural stem cell differentiation.
Purity:>95%
T3 (HB7470)
Description:Thyroid hormone. Frequently used in various stem cell protocols.
Purity:>98%
Venlafaxine hydrochloride (HB1743)
Description:Serotonin/norepinephrine re-uptake inhibitor. Affects differentiation of NSCs.
Purity:>98%
WHI-P 154 (HB1431)
Description:Non-selective JAK3 inhibitor and potent EGFR inhibitor. Induces neural progenitor cell differentiation.
Purity:>99%
XAV 939 (HB0660)
Description:Potent tankyrase inhibitor. Wnt/β-catenin signaling inhibitor.
Purity:>98%