Potent, cell-permeable Smo receptor agonist (Kd = 59 nM) and hedgehog (Hh) signaling activator. Counteracts cyclopamine inhibition of Smo. Acts as an Smo activator at low concentrations and an inhibitor at high concentrations. Also enhances neuronal differentiation of iPSC into dopaminergic neurons.
Solubility & Handling
Storage instructions
+4°C
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Y-27632 is a selective ROCK inhibitor. Frequently used 3D growth matrix component and for production of organoids. Also used when inducing neurons from fibroblasts. Manufactured to a high degree of optical purity.
![SAG [912545-86-9] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb3107.png "SAG [912545-86-9]")
Understanding purity and quality - a guide for life scientists
