Venlafaxine hydrochloride

(HB1743)
Technical documents: SDS CoA Datasheet

Product overview

Name Venlafaxine hydrochloride
Alternative names Wy 453
Purity >98%
Description Serotonin/norepinephrine re-uptake inhibitor. Affects differentiation of NSCs.
Write Your Own Review
You're reviewing:Venlafaxine hydrochloride
Rate this item:

Biological Data

Biological description Serotonin/norepinephrine re-uptake inhibitor. Shows ~ 30-fold higher affinity for SERT than NET (Ki values are 82 and 2480 nM respectively). Affects differentiation of NSCs. Shows antidepressant effects.

Solubility & Handling

Storage instructions Room temperature (protect from light)
Solubility overview Soluble in water (100mM) and in DMSO (50mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

=
x
x
More Info

Dilution

x
=
x
More Info

Chemical Data

Purity >98%
Chemical name 1-[2-(Dimethylamino)-1-(4-methoxyph enyl)ethyl]cyclohexanol hydrochloride
Molecular Weight 313.86
Chemical structure Venlafaxine hydrochloride | Wy 453 | [99300-78-4] Chemical Structure
Molecular Formula C17H27NO2.HCl
CAS Number 99300-78-4
PubChem identifier 62923
SMILES CN(C)CC(C1=CC=C(C=C1)OC)C2(CCCCC2)O.Cl
InChi InChI=1S/C17H27NO2.ClH/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14;/h7-10,16,19H,4-6,11-13H2,1-3H3;1H
InChiKey QYRYFNHXARDNFZ-UHFFFAOYSA-N
MDL number MFCD03658865
Appearance White solid
Publications
These publications cite the use of Venlafaxine hydrochloride purchased from Hello Bio:
  • Investigating the Behavioural and Electrophysiological Consequences of Early Life Stress

    Wilkinson et al (2021) Bristol University : Thesis
  • Comparison of conventional and rapid-acting antidepressants in a rodent probabilistic reversal learning task.

    Wilkinson et al. (2020) Brain Neurosci Adv 4 : 1-11
    PubMedID: 32219179
  • Comparison of acute treatment with delayed-onset versus rapid-acting antidepressants on effort-related choice behaviour

    Griesius S et al (2020) Psychopharmacology (Berl) 237(8) : 2381-2394
    PubMedID: 32435818
  • Evidence that neuropsychological deficits following early life adversity may underlie vulnerability to depression

    Stuart SA et al (2019) Neuropsychopharmacology 44(9) : 1623-1630
    PubMedID: 30978725

4 Item(s)