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Biological Data Biological description Serotonin/norepinephrine re-uptake inhibitor. Shows ~ 30-fold higher affinity for SERT than NET (Ki values are 82 and 2480 nM respectively). Affects differentiation of NSCs. Shows antidepressant effects.
Solubility & Handling Storage instructions Room temperature (protect from light)
Solubility overview Soluble in water (100mM) and in DMSO (50mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Chemical Data Chemical name 1-[2-(Dimethylamino)-1-(4-methoxyph enyl)ethyl]cyclohexanol hydrochloride
Chemical structure
Molecular Formula C17 H27 NO2 .HCl
SMILES CN(C)CC(C1=CC=C(C=C1)OC)C2(CCCCC2)O.Cl
InChi InChI=1S/C17H27NO2.ClH/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14;/h7-10,16,19H,4-6,11-13H2,1-3H3;1H
InChiKey QYRYFNHXARDNFZ-UHFFFAOYSA-N
Publications
These publications cite the use of Venlafaxine hydrochloride purchased from Hello Bio:
Investigating the Behavioural and Electrophysiological Consequences of Early Life Stress Wilkinson et al (2021) Bristol University : Thesis
Comparison of conventional and rapid-acting antidepressants in a rodent probabilistic reversal learning task. Wilkinson et al. (2020) Brain Neurosci Adv 4 : 1-11 Comparison of acute treatment with delayed-onset versus rapid-acting antidepressants on effort-related choice behaviour Griesius S et al (2020) Psychopharmacology (Berl) 237(8) : 2381-2394 Evidence that neuropsychological deficits following early life adversity may underlie vulnerability to depression Stuart SA et al (2019) Neuropsychopharmacology 44(9) : 1623-1630
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Serotonin/norepinephrine re-uptake inhibitor. Affects differentiation of NSCs.