Nuclear Receptors

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Nuclear hormone receptors (nuclear receptors) are specialised transcription factors which bind to specific sequences of DNA of particular target genes. They regulate transcription of these target genes in response to a variety of endogenous ligands. Nuclear receptors are classified into two major subfamilies: steroid and non-steroid hormone receptors. Steroid hormone receptors include receptors for estrogen (ER), androgen, glucocorticoid, mineralocorticoid and progesterone. Examples of non-steroid hormone receptors include thyroid receptors, retinoic acid receptors and peroxisome proliferator-activated receptors (PPAR). Researchers can save up to 50% on nuclear hormone receptor agonists, antagonists and modulators from Hello Bio - they are up to half the price of other suppliers.

Items 1-10 of 11

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  1. Eplerenone (HB2527)

    Description:

    Selective mineralcorticoid receptor antagonist

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $98
    Qty:
    Pack:
    50mg
    Price:
    $430
    Qty:
  2. FH 535 (HB0288)

    Description:

    Wnt/β-catenin inhibitor and PPARγ/δ antagonist.

    Purity:

    >99%

    Pack:
    50mg
    Price:
    $419
    Qty:
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    Description:

    Synthetic estrogen receptor ligand. Widely used in genome engineering (e.g. CreER/ CRISPR-Cas9).

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $50
    Qty:
    Pack:
    50mg
    Price:
    $178
    Qty:
  4. Description:

    Synthetic estrogen receptor ligand. Widely used in genome engineering (e.g. CreER/ CRISPR-Cas9).

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $39
    Qty:
    Pack:
    50mg
    Price:
    $151
    Qty:
  5. Description:

    Estrogen receptor (ER) antagonist and high affinity GPER agonist

    Purity:

    >99%

    Pack:
    1mg
    Price:
    $52
    Qty:
    Pack:
    10mg
    Price:
    $88
    Qty:
    Pack:
    50mg
    Price:
    $205
    Qty:
  6. Mifepristone (HB2783)

    Description:

    Potent glucocorticoid and progesterone receptor antagonist. Also used for gene editing as a mifepristone inducible Cas9 and Cpf1 CRISPR effector.

    Purity:

    >99%

    Pack:
    100mg
    Price:
    $70
    Qty:
  7. PHTPP (HB2503)

    Description:

    Selective ERβ estrogen receptor antagonist

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $174
    Qty:
    Pack:
    50mg
    Price:
    $674
    Qty:
  8. Spironolactone (HB2799)

    Description:

    Mineralocorticoid and androgen receptor antagonist

    Purity:

    >98%

    Pack:
    50mg
    Price:
    $45
    Qty:
  9. Stigmasterol (HB4095)

    Description:

    Phytosterol with anticancer and many other biological actions. Farnesoid X receptor antagonist.

    Purity:

    >95%

    Pack:
    5g
    Price:
    $200
    Qty:
  10. Tamoxifen (HB0601)

    Description:

    Estrogen receptor antagonist/ partial agonist. May be used in genome engineering (e.g. CreER/ CRISPR-Cas9).

    Purity:

    >99%

    Pack:
    100mg
    Price:
    $49
    Qty:

Items 1-10 of 11

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