Product overview
| Name | 17-AAG |
| Description | Selective Hsp90 inhibitor. Also protects neuroprogenitor cells against apoptosis. |
| Alternative names | Tanespimycin |
| Purity | >98% |
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Biological Data
| Biological description | Selective Hsp90 inhibitor. Potent, less toxic analog of geldanamycin. Also a telomerase activity inhibitor. Shows antitumor activity and induces apoptosis. Also protects neuroprogenitor cells against apoptosis. |
Solubility & Handling
| Storage instructions | -20°C |
| Solubility overview | Soluble in DMSO (100 mM) |
| Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
| Purity | >98% |
| Chemical name | 17-Demethoxy-17-(2-propenylamino)geldanamycin |
| Molecular Weight | 585.7 |
| Molecular Formula | C31H43N3O8 |
| CAS Number | 75747-14-7 |
| PubChem identifier | 433449 |
| SMILES | CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)NCC=C)C)OC)OC(=O)N)C)C)O)OC |
| InChiKey | AYUNIORJHRXIBJ-TXHRRWQRSA-N |
| MDL number | MFCD04973892 |
| Appearance | Purple |
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