Product overview

Name 17-AAG
Description Selective Hsp90 inhibitor. Also protects neuroprogenitor cells against apoptosis.
Alternative names Tanespimycin
Purity >98%
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Biological Data

Biological description Selective Hsp90 inhibitor. Potent, less toxic analog of geldanamycin. Also a telomerase activity inhibitor. Shows antitumor activity and induces apoptosis. Also protects neuroprogenitor cells against apoptosis.

Solubility & Handling

Storage instructions -20°C
Solubility overview Soluble in DMSO (100 mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Chemical Data

Chemical name 17-Demethoxy-17-(2-propenylamino)geldanamycin
Molecular Weight 585.7
Molecular Formula C31H43N3O8
CAS Number 75747-14-7
PubChem identifier 433449
SMILES CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)NCC=C)C)OC)OC(=O)N)C)C)O)OC
InChiKey AYUNIORJHRXIBJ-TXHRRWQRSA-N
MDL number MFCD04973892
Appearance Purple