AACOCF3

(HB2354)

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Product overview

Name AACOCF3
Alternative names Arachidonyl trifluoromethyl ketone
Description Selective cPLA2 inhibitor
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Biological Data

Biological description Selective cytosolic phospholipase A2 inhibitor (IC50 values are 1.5 and 6.0 µM for bovine brain cPLA2 and iPLA2 respectively). Also inhibits FAAH. Displaces [3H]CP-55940 binding to CB1 receptor (Ki = 0.65 µM). Increases aldosterone and corticosterone secretion.

Solubility & Handling

Storage instructions -20°C (desiccate)
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Chemical Data

Chemical name 1,1,1-Trifluoro-6Z,9Z,12Z,15Z-henei cosateraen-2-one
Molecular Weight 356.47
Chemical structure AACOCF3? Chemical Structure
Molecular Formula C21H31F3O
CAS Number 149301-79-1
PubChem identifier 5280436
SMILES O=C(C(F)(F)F)CCC\C=C/C\C=C/C/C=C\C/C=C\CCCCC
InChiKey PLWROONZUDKYKG-DOFZRALJSA-N