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Biological Data
| Biological description | PD-1/PD-L1 interaction inhibitor (Kd = 0.51µM at PD-L1). Inhibits tumor growth and prolongs survival time of mice in vivo.
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Solubility & Handling
| Storage instructions | -20°C |
| Solubility overview | Soluble in water (2 mg/ml) |
| Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
| Molecular Formula | C70H98N20O21 |
References for (D)-PPA 1
References are publications that support the biological activity of the product
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PD-1/PD-L1 pathway and angiogenesis dual recognizable nanoparticles for enhancing chemotherapy of malignant cancer.
Sun Z et al (2018) Drug delivery 25 : 1746-1755 -
Blocking of the PD-1/PD-L1 Interaction by a D-Peptide Antagonist for Cancer Immunotherapy.
Chang HN et al (2015) Angewandte Chemie (International ed. in English) 54 : 11760-4
PD-1/PD-L1 interaction inhibitor
Understanding purity and quality - a guide for life scientists
