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Biological Data Biological description PD-1/PD-L1 interaction inhibitor (Kd = 0.51µM at PD-L1). Inhibits tumor growth and prolongs survival time of mice in vivo.
Solubility & Handling Storage instructions -20°C
Solubility overview Soluble in water (2 mg/ml)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Chemical Data Molecular Formula C70 H98 N20 O21
References for (D)-PPA 1 References are publications that support the biological activity of the product
PD-1/PD-L1 pathway and angiogenesis dual recognizable nanoparticles for enhancing chemotherapy of malignant cancer. Sun Z et al (2018) Drug delivery 25 : 1746-1755 Blocking of the PD-1/PD-L1 Interaction by a D-Peptide Antagonist for Cancer Immunotherapy. Chang HN et al (2015) Angewandte Chemie (International ed. in English) 54 : 11760-4
PD-1/PD-L1 interaction inhibitor
Understanding purity and quality - a guide for life scientists
