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Biological Data

Biological description PD-1/PD-L1 interaction inhibitor (Kd = 0.51µM at PD-L1). Inhibits tumor growth and prolongs survival time of mice in vivo.

Solubility & Handling

Storage instructions -20°C
Solubility overview Soluble in water (2 mg/ml)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.



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Chemical Data

Molecular Weight 1555.67
Molecular Formula C70H98N20O21
CAS Number 1620813-53-7

References for (D)-PPA 1

References are publications that support the biological activity of the product
  • PD-1/PD-L1 pathway and angiogenesis dual recognizable nanoparticles for enhancing chemotherapy of malignant cancer.

    Sun Z et al (2018) Drug delivery 25 : 1746-1755
  • Blocking of the PD-1/PD-L1 Interaction by a D-Peptide Antagonist for Cancer Immunotherapy.

    Chang HN et al (2015) Angewandte Chemie (International ed. in English) 54 : 11760-4

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