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A-7 hydrochloride

(HB0097)
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Product overview

Name A-7 hydrochloride
Description Potent, cell-permeable calmodulin (CaM) antagonist
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (2)
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Biological Data

Biological description Potent calmodulin antagonist. Cell permeable. Napthalenesulfonamide W-7 analog. Inhibits calmodulin activated PDE activity (IC50 = 3 µM).

Solubility & Handling

Solubility overview Soluble in DMSO (50mM)
Storage instructions Room temperature
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Chemical name N-(10-Aminodecyl)-5-chloro-1-naphthalenesulfonamide hydrochloride
Molecular Weight 433.44
Chemical structure A-7 hydrochloride [79127-24-5] Chemical Structure
Molecular Formula C20H29ClN2O2S.HCl
CAS Number 79127-24-5
PubChem identifier 44119113
SMILES C1=CC2=C(C=CC=C2Cl)C(=C1)S(=O)(=O)NCCCCCCCCCCN.Cl
InChiKey XDJCAQBTSCRBHS-UHFFFAOYSA-N

References for A-7 hydrochloride

References are publications that support the biological activity of the product

  • Direct interaction of calmodulin antagonists with Ca2+/calmodulin-dependent cyclic nucleotide phosphodiesterase.

    Itoh H et al (1984) J Biochem 96(6) : 1721-6.
    Read more (PubMedID: 6099352)

  • Naphthalenesulfonamides as calmodulin antagonists.

    Hidaka H et al (1983) Methods Enzymol 102 : 185-94.
    Read more (PubMedID: 6139736)

2 Item(s)

Grouped product items
Order: HB0097
Pack PriceQty
25mg
$370
Potent, cell-permeable calmodulin (CaM) antagonist
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

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