Group I (mGlu5, mGlu1)

Group I metabotropic glutamate receptors (mGlu1, mGlu5) are coupled with phospholipase C (PLC) via Gq proteins; activation causes increased levels of IP3 and diacylglycerol, with intracellullar Ca2+ release and protein kinase C (PKC) activation. Group I receptors are predominantly located post synaptically. Researchers can save 50% on group I metabotropic glutamate receptor agonists, antagonists, positive allosteric modulators (PAMs) and negative allosteric modulators (NAMs) from Hello Bio - they are up to half the price of other suppliers.

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Items 11-20 of 21

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  1. Description:

    Novel, inactive photocaged derivative of raseglurant which can be uncaged with violet light. Shows light-dependent analgesic activity in vivo.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $68
    Qty:
    Pack:
    5mg
    Price:
    $321
    Qty:
  2. Pack:
    10mg
    Price:
    $192
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    Pack:
    25mg
    Price:
    $441
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    Pack:
    50mg
    Price:
    $816
    Qty:
  3. Description:

    Potent, highly selective mGlu1a antagonist. Water soluble.

    Pack:
    10mg
    Price:
    $136
    Qty:
    Pack:
    50mg
    Price:
    $517
    Qty:
  4. Pack:
    5mg
    Price:
    $74
    Qty:
    Pack:
    10mg
    Price:
    $141
    Qty:
    Pack:
    25mg
    Price:
    $319
    Qty:
    Pack:
    50mg
    Price:
    $616
    Qty:
  5. Description:

    Potent, selective mGluR5 antagonist / mGluR4 positive allosteric modulator

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $123
    Qty:
    Pack:
    50mg
    Price:
    $458
    Qty:
  6. Pack:
    10mg
    Price:
    $132
    Qty:
    Pack:
    50mg
    Price:
    $498
    Qty:
    Pack:
    10mM (add 1ml water)
    Price:
    $52
    Qty:
  7. Pack:
    5mg
    Price:
    $90
    Qty:
    Pack:
    10mg
    Price:
    $157
    Qty:
    Pack:
    50mg
    Price:
    $622
    Qty:
  8. Pack:
    10mg
    Price:
    $133
    Qty:
    Pack:
    50mg
    Price:
    $542
    Qty:
  9. Pack:
    50mg
    Price:
    $510
    Qty:
  10. Pack:
    10mg
    Price:
    $158
    Qty:
    Pack:
    50mg
    Price:
    $649
    Qty:
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