Group I (mGlu5, mGlu1)

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Group I metabotropic glutamate receptors (mGlu1, mGlu5) are coupled with phospholipase C (PLC) via Gq proteins; activation causes increased levels of IP3 and diacylglycerol, with intracellullar Ca2+ release and protein kinase C (PKC) activation. Group I receptors are predominantly located post synaptically. Researchers can save 50% on group I metabotropic glutamate receptor agonists, antagonists, positive allosteric modulators (PAMs) and negative allosteric modulators (NAMs) from Hello Bio - they are up to half the price of other suppliers.

Items 11-20 of 21

Set Descending Direction
  1. Description:

    Novel, inactive photocaged derivative of raseglurant which can be uncaged with violet light. Shows light-dependent analgesic activity in vivo.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $60
    Qty:
    Pack:
    5mg
    Price:
    $284
    Qty:
  2. Pack:
    10mg
    Price:
    $169
    Qty:
    Pack:
    25mg
    Price:
    $388
    Qty:
    Pack:
    50mg
    Price:
    $720
    Qty:
  3. Description:

    Potent, highly selective mGlu1a antagonist. Water soluble.

    Pack:
    10mg
    Price:
    $120
    Qty:
    Pack:
    50mg
    Price:
    $456
    Qty:
  4. Pack:
    5mg
    Price:
    $65
    Qty:
    Pack:
    10mg
    Price:
    $124
    Qty:
    Pack:
    25mg
    Price:
    $280
    Qty:
    Pack:
    50mg
    Price:
    $544
    Qty:
  5. Description:

    Potent, selective mGluR5 antagonist / mGluR4 positive allosteric modulator

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $107
    Qty:
    Pack:
    50mg
    Price:
    $399
    Qty:
  6. Pack:
    10mg
    Price:
    $116
    Qty:
    Pack:
    50mg
    Price:
    $439
    Qty:
    Pack:
    10mM (add 1ml water)
    Price:
    $45
    Qty:
  7. Pack:
    5mg
    Price:
    $79
    Qty:
    Pack:
    10mg
    Price:
    $138
    Qty:
    Pack:
    50mg
    Price:
    $549
    Qty:
  8. Pack:
    10mg
    Price:
    $134
    Qty:
    Pack:
    50mg
    Price:
    $547
    Qty:
  9. Pack:
    50mg
    Price:
    $450
    Qty:
  10. Pack:
    10mg
    Price:
    $139
    Qty:
    Pack:
    50mg
    Price:
    $573
    Qty:
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