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(S)-4-Carboxyphenylglycine product vial image | Hello Bio
(S)-4-Carboxyphenylglycine product vial image | Hello Bio
Biological Data
| Biological description | Competitive and selective group 1 mGluR antagonist. Shows selectivity for mGluR1a over mGluR5a/5b. Displays preventative vasospasm properties. |
Solubility & Handling
| Storage instructions | Room temperature |
| Solubility overview | Soluble in NaOH(aq) (100mM, gentle warming) |
| Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
| Chemical structure | ![(S)-4-Carboxyphenylglycine [134052-73-6] Chemical Structure](data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR4nGP6zwAAAgcBApocMXEAAAAASUVORK5CYII= "(S)-4-Carboxyphenylglycine [134052-73-6]") |
| Molecular Formula | C9H9NO4 |
| PubChem identifier | 5311459 |
| SMILES | [H][C@@](N)(C(O)=O)C1=CC=C(C(O)=O)C=C1 |
| InChiKey | VTMJKPGFERYGJF-ZETCQYMHSA-N |
References for (S)-4-Carboxyphenylglycine
References are publications that support the biological activity of the product
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A glutamate receptor antagonist, S-4-carboxyphenylglycine (S-4-CPG), inhibits vasospasm after subarachnoid hemorrhage in haptoglobin 2-2 mice [corrected].
Garzon-Muvdi T et al (2013) Neurosurgery 73(4) : 719-28 -
Antagonist activity of alpha-substituted 4-carboxyphenylglycine analogues at group I metabotropic glutamate receptors expressed in CHO cells.
Doherty AJ et al (1999) Br J Pharmacol 126(1) : 205-10. -
Phenylglycine derivatives discriminate between mGluR1- and mGluR5-mediated responses.
Brabet I et al (1995) Neuropharmacology 34(8) : 895-903.
Competitive, selective group 1 mGlu antagonist
![(S)-4-Carboxyphenylglycine [134052-73-6] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb0049.png "(S)-4-Carboxyphenylglycine [134052-73-6]")
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