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(S)-4-Carboxyphenylglycine

(HB0049)
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Technical documents: SDS Datasheet
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Product overview

Name (S)-4-Carboxyphenylglycine
Purity >99%
Description Competitive, selective group 1 mGlu antagonist
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (3) Reviews References (3)
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Images

(S)-4-Carboxyphenylglycine product vial image | Hello Bio
(S)-4-Carboxyphenylglycine product vial image | Hello Bio

(S)-4-Carboxyphenylglycine product vial image | Hello Bio

(S)-4-Carboxyphenylglycine product vial image | Hello Bio

Biological Data

Biological description Competitive and selective group 1 mGluR antagonist. Shows selectivity for mGluR1a over mGluR5a/5b. Displays preventative vasospasm properties.

Solubility & Handling

Solubility overview Soluble in NaOH(aq) (100mM, gentle warming)
Storage instructions Room temperature
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >99%
Molecular Weight 195.17
Chemical structure (S)-4-Carboxyphenylglycine [134052-73-6] Chemical Structure
Molecular Formula C9H9NO4
CAS Number 134052-73-6
PubChem identifier 5311459
SMILES [H][C@@](N)(C(O)=O)C1=CC=C(C(O)=O)C=C1
InChiKey VTMJKPGFERYGJF-ZETCQYMHSA-N

References for (S)-4-Carboxyphenylglycine

References are publications that support the biological activity of the product

  • A glutamate receptor antagonist, S-4-carboxyphenylglycine (S-4-CPG), inhibits vasospasm after subarachnoid hemorrhage in haptoglobin 2-2 mice [corrected].

    Garzon-Muvdi T et al (2013) Neurosurgery 73(4) : 719-28
    Read more (PubMedID: 23842553)

  • Antagonist activity of alpha-substituted 4-carboxyphenylglycine analogues at group I metabotropic glutamate receptors expressed in CHO cells.

    Doherty AJ et al (1999) Br J Pharmacol 126(1) : 205-10.
    Read more (PubMedID: 10051137)

  • Phenylglycine derivatives discriminate between mGluR1- and mGluR5-mediated responses.

    Brabet I et al (1995) Neuropharmacology 34(8) : 895-903.
    Read more (PubMedID: 8532171)

3 Item(s)

Grouped product items
Order: HB0049
Pack PriceQty
5mg
$136
Competitive, selective group 1 mGlu antagonist
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

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