Product overview

Name L-Cysteinesulfinic acid monohydrate
Description mGlu / mGlu5a agonist
Alternative names L-CSA
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Biological Data

Biological description mGlu and mGlu5a receptor agonist in RGT cell lines. Also acts as a NMDA receptor agonist and PLD-coupled mGlu receptor agonist.

Solubility & Handling

Storage instructions -20°C (desiccate)
Solubility overview Soluble in water (100mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Molecular Weight 171.17
Chemical structure L-Cysteinesulfinic acid monohydrate  [1115-65-7] Chemical Structure
Molecular Formula C3H7NO4S.H2O
CAS Number 1115-65-7
PubChem identifier 1549098
SMILES [H][C@](N)(CS(O)=O)C(O)=O
InChiKey ADVPTQAUNPRNPO-REOHCLBHSA-N

References for L-Cysteinesulfinic acid monohydrate

References are publications that support the biological activity of the product
  • Metabotropic glutamate receptors activate phospholipase D in astrocytes through a protein kinase C-dependent and Rho-independent pathway.

    Servitja JM et al (2003) Neuropharmacology 44(2) : 171-80.
  • Sulphur-containing amino acids are agonists for group 1 metabotropic receptors expressed in clonal RGT cell lines.

    Kingston AE et al (1998) Neuropharmacology 37(3) : 277-87.
  • L-cysteine sulfinic acid as an endogenous agonist of a novel metabotropic receptor coupled to stimulation of phospholipase D activity.

    Boss V et al (1994) Mol Pharmacol 45(6) : 1177-82.
  • Sulphur-containing excitatory amino acid-stimulated inositol phosphate formation in primary cultures of cerebellar granule cells is mediated predominantly by N-methyl-D-aspartate receptors.

    Gorman A et al (1994) Neuroscience 59(2) : 299-308.