Ligand-gated ion channel

Ligand-gated ion channels (also known as ionotropic receptors) are transmembrane ion channel proteins that allow passage of ions upon activation by a specific chemical. Ligand-gated ion channels include ionotropic glutamate receptors (AMPA, kainate and NMDA receptors), GABAA, GABAA-ρ, Glycine, 5-HT3, HCN, acetylcholine nicotinic and purinergic (P2X) receptors. Commonly used ligands include D-AP5, NBQX, kainic acid, and gabazine. Researchers can save up to 50% on ligand-gated ion channel (ionotropic receptor) agonists, antagonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.

View products: Ionotropic glutamate | ACh Nicotinic | AMPA | GABAA | Glycine | 5-HT3Kainate | NMDA | P2X | Neuroscience Research Tools

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  2. Mifepristone (HB2783)

    Description:

    Potent glucocorticoid and progesterone receptor antagonist. Also used for gene editing as a mifepristone inducible Cas9 and Cpf1 CRISPR effector.

    Purity:

    >99%

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    100mg
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    5-HT and norepinephrine re-uptake inhibitor (SNRI)

    Purity:

    >99%

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    $126
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    $806
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  5. Description:

    Highly selective, pan-Akt inhibitor. Autophagy and apoptosis inducer. Orally bioavailable.

    Purity:

    >98%

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    10mM solution (in 1mL DMSO)
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  6. Description:

    Selective leukotriene LTD4 receptor antagonist. Potent MRP1 inhibitor.

    Purity:

    >97%

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    $284
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    10mM (add 1ml water)
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    $263
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    20mM (add 1ml water)
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    $75
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    10mg
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