Product overview
| Name | Miltefosine |
| Description | Akt inhibitor |
| Purity | >98% |
Write Your Own Review
Biological Data
| Biological description | Akt inhibitor. Inhibits T-cell proliferation and HIV-1 cell survival and production. Displays anti-inflammatory and anticancer properties with broad spectrum of fungicidal and antiamoebae activities. Blood brain barrier permeable. |
Solubility & Handling
| Storage instructions | -20°C |
| Solubility overview | Soluble in water (25 mM) |
| Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
| Chemical name | 1-Hexadecylphosphorylcholine |
| Molecular Weight | 407.6 |
| Chemical structure | ![Miltefosine [58066-85-6] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb0412.png "Miltefosine [58066-85-6]") |
| Molecular Formula | C21H46NO4P |
| CAS Number | 58066-85-6 |
| PubChem identifier | 3599 |
| SMILES | CCCCCCCCCCCCCCCCOP(=O)([O-])OCC[N+](C)(C)C |
References for Miltefosine
References are publications that support the biological activity of the product
-
Miltefosine suppresses inflammation in a mouse model of inflammatory bowel disease.
Verhaar AP et al (2013) Inflamm Bowel Dis 19(9) : 1974-82. -
Miltefosine enhances phagocytosis but decreases nitric oxide production by peritoneal macrophages of C57BL/6 mice.
Ponte CB et al (2012) Int Immunopharmacol 13(1) : 114-9. -
Akt inhibitors as an HIV-1 infected macrophage-specific anti-viral therapy.
Chugh P et al (2008) Retrovirology 5 : 11
Understanding purity and quality - a guide for life scientists