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(-)-MK 801 maleate (Less active enantiomer of (+)-MK 801)

(HB0003)
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Product overview

Name (-)-MK 801 maleate (Less active enantiomer of (+)-MK 801)
Alternative names Dizocilpine maleate, Dizocilpine
Purity >99%
Description

Less active enantiomer of (+)-MK 801. NMDA receptor antagonist.

Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (4) Reviews References (2) Frequently bought together
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(-)-MK 801 maleate product vial image | Hello Bio
(-)-MK 801 maleate product vial image | Hello Bio

(-)-MK 801 maleate product vial image | Hello Bio

(-)-MK 801 maleate product vial image | Hello Bio

Biological Data

Biological description

NMDA receptor antagonist which is the less active enantiomer of (+)-MK 801 maleate. It shows approximately 10-fold reduction in potency compared to (+)-MK 801 maleate.

Solubility & Handling

Storage instructions Room temperature
Solubility overview Soluble in water (25mM, gentle warming)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >99%
Chemical name (5R,10S)-(-)-5-Methyl-10,11-dihydro -5H-dibenzo[a,d]cylcohepten-5,10-imine maleate
Molecular Weight 337.37
Chemical structure (-)-MK 801 maleate [121917-57-5] Chemical Structure
Molecular Formula C16H15N.C4H4O4
CAS Number 121917-57-5
PubChem identifier 16219612
SMILES O=C(O)/C=CC(=O)O.C[C@]42N[C@@H](Cc1ccccc12)c3ccccc34
Source Synthetic
InChi InChI=1S/C16H15N.C4H4O4/c1-16-13-8-4-2-6-11(13)10-15(17-16)12-7-3-5-9-14(12)16;5-3(6)1-2-4(7)8/h2-9,15,17H,10H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/t15-,16+;/m0./s1
InChiKey QLTXKCWMEZIHBJ-FWHYOZOBSA-N
Appearance White solid

References for (-)-MK 801 maleate (Less active enantiomer of (+)-MK 801)

References are publications that support the biological activity of the product

  • Effects of MK-801 stereoisomers on schedule-controlled behavior in rats.

    Genovese RF et al (1991) Psychopharmacology (Berl) 105(4) : 477-80.
    Read more (PubMedID: 1771215)

  • The effects of dizocilpine maleate (MK-801), an antagonist of the N-methyl-D-aspartate receptor, on neurologic recovery and histopathology following complete cerebral ischemia in primates.

    Lanier WL et al (1990) J Cereb Blood Flow Metab 10(2) : 252-61.
    Read more (PubMedID: 2154509)

2 Item(s)

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Order: HB0003
Pack PriceQty
10mg
$60
50mg
$263
20mM (add 1ml water)
$75

Less active enantiomer of (+)-MK 801. NMDA receptor antagonist.

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Standard: $35

Hazardous: $35

Shipped on ice: $35

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