Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. Niclosamide (HB1435)

    Description:

    STAT3 signaling pathway inhibitor. Antineoplastic against AML stem cells.

    Purity:

    >98%

    Pack:
    50mg
    Price:
    $145
    Qty:
  2. Nocodazole (HB3999)

    Description:

    Mitosis inhibitor, widely used as a cell cycle synchronizing agent. Enhances HDR efficiency and increases Cas9-mediated gene editing frequencies.

    Purity:

    >98%

    Pack:
    50mg
    Price:
    $407
    Qty:
  3. Pack:
    10mg
    Price:
    $215
    Qty:
    Pack:
    50mg
    Price:
    $768
    Qty:
  4. NSC 74859 (HB1436)

    Description:

    Selective STAT3 inhibitor

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $115
    Qty:
    Pack:
    25mg
    Price:
    $460
    Qty:
  5. Pack:
    100mg
    Price:
    $42
    Qty:
    Pack:
    500mg
    Price:
    $205
    Qty:
  6. Pack:
    100mg
    Price:
    $64
    Qty:
  7. Description:

    Oxazole Yellow iodide is also known as Yo-Pro-1. It is a commonly used apoptosis marker.

    Pack:
    1mg
    Price:
    $208
    Qty:
  8. Description:

    Oxazole Yellow iodide is also known as Yo-Pro-1. It is a commonly used apoptosis marker. 1mM solution (in 1mL DMSO)

    Pack:
    1mL
    Price:
    $274
    Qty:
  9. Pam2CSK4 (HB3086)

    Description:

    TLR2/6 activator. Induces potent NF-κB activation and cytokine production.

    Pack:
    1mg
    Price:
    $159
    Qty:
  10. Pam3CSK4 (HB3428)

    Description:

    TLR1/TLR2 agonist and potent NF-κB activator. Induces cytokine production.

    Pack:
    1mg
    Price:
    $153
    Qty:
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