Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

Show/Hide Filters

Items 101-110 of 191

Set Descending Direction
  1. Description:

    Novel, intracellular covalent chemokine CCR2 negative allosteric modulator (NAM). Binds irreversibly.

    Pack:
    50μg
    Price:
    $275
    Qty:
  2. Pack:
    5mg
    Price:
    Qty:
    Pack:
    25mg
    Price:
    $184
    Qty:
  3. 3-Methyladenine (HB2267)

    Description:

    PI-3K inhibitor

    Purity:

    >99%

    Pack:
    50mg
    Price:
    $120
    Qty:
    Pack:
    100mg
    Price:
    $172
    Qty:
  4. Description:

    SARS-CoV Mpro FRET substrate suitable for measuring Mpro & SARS-Cov Mpro protease activity

    Pack:
    1mg
    Price:
    $354
    Qty:
  5. Description:

    Potent, selective NLRP3 inflammasome inhibitor

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $93
    Qty:
    Pack:
    5mg
    Price:
    $370
    Qty:
    Pack:
    10mg
    Price:
    $597
    Qty:
  6. Description:

    Cx36 and Cx50 gap channel blocker. Antimalarial, antischistosomal and antiviral.

    Purity:

    >98%

    Pack:
    100mg
    Price:
    $55
    Qty:
  7. MEGA-8 (HB3972)

    Description:

    Non-ionic,water-soluble detergent with nondenaturing properties

    Purity:

    >99%

    Pack:
    5g
    Price:
    $284
    Qty:
  8. Pack:
    100mg
    Price:
    $69
    Qty:
    Pack:
    100mM (add 1ml water)
    Price:
    $43
    Qty:
  9. MHY 1485 (HB7154)

    Description:

    mTOR activator and autophagy inhibitor. Cell-permeable.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $58
    Qty:
    Pack:
    50mg
    Price:
    $182
    Qty:
  10. Mifepristone (HB2783)

    Description:

    Potent glucocorticoid and progesterone receptor antagonist. Also used for gene editing as a mifepristone inducible Cas9 and Cpf1 CRISPR effector.

    Purity:

    >99%

    Pack:
    100mg
    Price:
    $86
    Qty:
Page