Product overview

Name Ouabain
Alternative names g-strophanthin
Purity >98%
Description Selective Na+ / K+ ATPase inhibitor. Shows antiviral activity.
Write Your Own Review
You're reviewing:Ouabain
Rate this item:


Ouabain product vial image | Hello Bio

Biological Data

Biological description

Selective Na+ / K+ ATPase inhibitor. Thought to act as a proliferative agent; promotes cardiac and vascular myocyte cell growth. Shows positive inotropic, vasoconstrictive and hypertensive actions.

Also shows antiviral activity (e.g. reported anti-MERS-CoV activity in Vero cells)

Solubility & Handling

Storage instructions -20°C (desiccate)
Solubility overview Soluble in water (10mM) and in DMSO (100mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.



More Info


More Info

Chemical Data

Purity >98%
Chemical name 3-[(6-Deoxy-α-L-mannopyranosyl)oxy]-1,5,11α,14,19-pentahydoxycard-20(22)-enolide
Molecular Weight 584.66
Chemical structure Ouabain  [630-60-4] Chemical Structure
Molecular Formula C29H44O12.8H2O
CAS Number 630-60-4
PubChem identifier 439501
SMILES C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@H]2C[C@H]([C@@]3([C@@H]4[C@@H](CC[C@@]3(C2)O)[C@]5(CC[C@@H]([C@]5(C[C@H]4O)C)C6=CC(=O)OC6)O)CO)O)O)O)O
InChi InChI=1S/C29H44O12/c1-13-22(34)23(35)24(36)25(40-13)41-15-8-19(32)28(12-30)21-17(3-5-27(28,37)9-15)29(38)6-4-16(14-7-20(33)39-11-14)26(29,2)10-18(21)31/h7,13,15-19,21-25,30-32,34-38H,3-6,8-12H2,1-2H3/t13-,15-,16+,17+,18+,19+,21+,22-,23+,24+,25-,26+,27-,28
MDL number MFCD00149240
Appearance White solid

References for Ouabain

References are publications that support the biological activity of the product
  • Screening of FDA-approved drugs using a MERS-CoV clinical isolate from South Korea identifies potential therapeutic options for COVID-19

    Ko et al (2020) bioRxiv : Preprint
  • Increased constrictor tone induced by ouabain treatment in rats.

    Pulgar VM et al (2013) J Cardiovasc Pharmacol 62(2) : 174-83.
  • Effect of m-calpain in PKCalpha-mediated proliferation of pulmonary artery smooth muscle cells by low dose of ouabain.

    Shaikh S et al (2013) Indian J Biochem Biophys 50(5) : 419-27.
  • Different roles of the cardiac Na+/Ca2+-exchanger in ouabain-induced inotropy, cell signaling, and hypertrophy.

    Bai Y et al (2013) Am J Physiol Heart Circ Physiol 304(3) : H427-35.

4 Item(s)